[不同个体发育阶段大鼠性腺细胞中配体蛋白的定位]
[Ligandin localization in the gonadal cells of rats at various stages of ontogeny].
作者信息
Bannikov G A, Chipysheva T A
出版信息
Ontogenez. 1979;10(5):468-75.
PMID:386201
Abstract
Ligandin, a protein binding some carcinogens, steroids and other substances in the rat liver, has been found by means of indirect immunofluorescence in the gonad cells of different types: embryonic and mature Leidig cells in testes, ovarian thecal cells at the maturation stages (theca interna, atretic follicles and interstitial cells) and luteal cells of corpus luteum at pregnancy. Ligandin is found, thus, in cells which belong to various lines of cell differentiation. The functional role of ligandin is discussed.
摘要
配体蛋白是一种能与大鼠肝脏中的某些致癌物、类固醇及其他物质结合的蛋白质，通过间接免疫荧光法已在不同类型的性腺细胞中发现它的存在：睾丸中的胚胎型和成熟型莱迪希细胞、成熟阶段的卵巢膜细胞（卵泡内膜、闭锁卵泡和间质细胞）以及妊娠黄体的黄体细胞。因此，在属于不同细胞分化谱系的细胞中都发现了配体蛋白。文中还讨论了配体蛋白的功能作用。
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