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细菌病原体的最新情况:毒力与耐药性

Update on bacterial pathogens: virulence and resistance.

作者信息

Cercenado Emilia, Garau Javier, Almirante Benito, Ramón Azanza José, Cantón Rafael, Cisterna Ramón, María Eiros José, Fariñas Carmen, Fortún Jesús, Gudiol Francisco, Mensa José, Pachón Jerónimo, Pascual Álvaro, Luis Pérez José, Rodríguez Alejandro, Sánchez Miguel, Vila Jordi

机构信息

Servicio de Microbiología. Hospital General Universitario Gregorio Marañón. Madrid. Spain.

Servicio de Enfermedades Infecciosas. Hospital Mutua de Terrassa. Barcelona. Spain.

出版信息

Enferm Infecc Microbiol Clin. 2008 Apr;26:3-21. doi: 10.1016/S0213-005X(08)76378-X. Epub 2009 May 13.

DOI:10.1016/S0213-005X(08)76378-X
PMID:38620184
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7130156/
Abstract

The present article is an update of the literature on bacterial pathogens. Recognizing the interest and scientific and public health importance of infections produced by bacterial pathogens with new virulence mechanisms and/or new mechanisms of resistance to antimicrobial agents, a multidisciplinary group of Spanish physicians and microbiologists organized a joint session and revised the most important papers produced in the field during 2006. Each article was analyzed and discussed by one of the members of the panel. This paper focus on a variety of diseases that pose major clinical and public health challenges today; and include infections produced by community-acquired methicillin-resistant and small colony variants, infections produced by multiply resistant coagulase-negative staphylococci, pneumococcal infections, human listeriosis, meningococcal disease, , pertussis, , ESBL-producing organisms, and infections due to non-fermenters. After a review of the state of the art, papers selected in this field are discussed.

摘要

本文是关于细菌病原体文献的更新。鉴于具有新毒力机制和/或新抗菌耐药机制的细菌病原体所引发感染的研究兴趣以及其在科学和公共卫生方面的重要性,一群西班牙医生和微生物学家组成的多学科团队组织了一次联合会议,并对2006年该领域发表的最重要论文进行了修订。每篇文章都由小组中的一名成员进行分析和讨论。本文聚焦于当今面临重大临床和公共卫生挑战的多种疾病;包括社区获得性耐甲氧西林菌和小菌落变异株引发的感染、多重耐药凝固酶阴性葡萄球菌引发的感染、肺炎球菌感染、人类李斯特菌病、脑膜炎球菌病、百日咳、产超广谱β-内酰胺酶(ESBL)的微生物引发的感染以及非发酵菌引发的感染。在回顾了当前的技术水平之后,对该领域挑选出的论文进行了讨论。

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本文引用的文献

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Molecular epidemiology of methicillin-resistant Staphylococcus aureus in Spain: a multicentre prevalence study (2002).西班牙耐甲氧西林金黄色葡萄球菌的分子流行病学:一项多中心患病率研究(2002年)
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Genetic polymorphism of the binding domain of surfactant protein-A2 increases susceptibility to meningococcal disease.表面活性蛋白A2结合域的基因多态性增加了对脑膜炎球菌病的易感性。
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Bacteremia due to extended-spectrum beta -lactamase-producing Escherichia coli in the CTX-M era: a new clinical challenge.CTX-M 时代产超广谱β-内酰胺酶大肠埃希菌所致菌血症:一项新的临床挑战。
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Serogroup C meningococcal glycoconjugate vaccine in adolescents: persistence of bactericidal antibodies and kinetics of the immune response to a booster vaccine more than 3 years after immunization.青少年C群脑膜炎球菌结合疫苗:免疫接种3年多后杀菌抗体的持久性及对加强疫苗免疫反应的动力学
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[Bordetella pertussis detection by real-time PCR, immunofluorescence and culture: prospective evaluation and molecular epidemiology].[通过实时聚合酶链反应、免疫荧光和培养法检测百日咳博德特氏菌:前瞻性评估与分子流行病学]
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