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废水中抗抑郁药的监测:概述、提取与检测

Antidepressants surveillance in wastewater: Overview extraction and detection.

作者信息

Melchor-Martínez Elda M, Jiménez-Rodríguez Mildred G, Martínez-Ruiz Manuel, Peña-Benavides Samantha Ayde, Iqbal Hafiz M N, Parra-Saldívar Roberto, Sosa-Hernández Juan Eduardo

机构信息

Tecnologico de Monterrey, School of Engineering and Sciences, Ave. Eugenio Garza Sada 2501, CP 64849, Monterrey, NL, Mexico.

出版信息

Case Stud Chem Environ Eng. 2021 Jun;3:100074. doi: 10.1016/j.cscee.2020.100074. Epub 2020 Dec 24.

Abstract

The COVID-19 pandemic has been one of the biggest challenges worldwide. The psychological disorders associated with the pandemic causing depression, insomnia, post-traumatic stress disorder (PTSD) and anxiety reduce emotional stability. Different antidepressant drugs with several mechanisms of action are used with a prescription. The excretion of the compounds and their metabolites reach municipal wastewaters and enter sewage treatment plants with a low rate of remotion of pharmaceutical compounds and the releasing on the environment. Several effects on aquatic species exposed to antidepressants have been reported as the impact in gene transcription, reproduction cycles, predator defense, and motility. The aim of this work is to resume the common antidepressants detected in wastewater around the world and show the increment of its use during SARS-CoV-2 crisis.

摘要

新冠疫情一直是全球面临的最大挑战之一。与疫情相关的心理障碍会导致抑郁、失眠、创伤后应激障碍(PTSD)和焦虑,从而降低情绪稳定性。不同作用机制的抗抑郁药物需凭处方使用。这些化合物及其代谢产物会排放到城市污水中,并进入污水处理厂,而药物化合物的去除率较低,会释放到环境中。据报道,接触抗抑郁药对水生生物有多种影响,包括对基因转录、繁殖周期、捕食者防御和运动能力的影响。这项工作的目的是总结在世界各地废水中检测到的常见抗抑郁药,并展示在新冠病毒危机期间其使用量的增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3170/7969484/63a41886bc07/fx1.jpg

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