Membrilla J A, Caronna E, Trigo-López J, González-Martínez A, Layos-Romero A, Pozo-Rosich P, Guerrero-Peral Á, Gago-Veiga A B, Andrés-López A, Díaz de Terán J
Unidad de Cefaleas Complejas y Dolor Neuropático, Servicio de Neurología, Hospital Universitario La Paz, Madrid, Spain.
Servicio de Neurología, Hospital Universitario Vall d'Hebron, Departamento de Medicina, Universidad Autónoma de Barcelona, Barcelona, Spain.
Neurol Perspect. 2021 Dec;1:S31-S36. doi: 10.1016/j.neurop.2021.10.003. Epub 2021 Dec 14.
SARS-CoV-2 is the virus responsible for the COVID-19 pandemic. The acute infection is characterised not only by respiratory symptoms, but also by multiple systemic manifestations, including neurological symptoms. Among these, headache is a frequent complaint. As the pandemic progresses and the population of patients recovering from COVID-19 grows, it is becoming apparent that the headache present in the acute stage of the infection may persist for an indeterminate period, becoming a major problem for the patient and potentially leading to disability. In this review we describe the pathophysiological and clinical aspects of persistent headache after COVID-19 based on the information currently available in the literature and the authors' clinical experience.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）是引发新型冠状病毒肺炎（COVID-19）大流行的病毒。急性感染不仅以呼吸道症状为特征，还伴有多种全身表现，包括神经症状。其中，头痛是常见的主诉。随着疫情的发展以及从COVID-19中康复的患者数量增加，越来越明显的是，感染急性期出现的头痛可能会持续一段不确定的时间，成为患者的主要问题，并可能导致残疾。在本综述中，我们根据目前文献中的信息以及作者的临床经验，描述COVID-19后持续性头痛的病理生理和临床方面。
