Department of Urology, Borgo Trento Hospital, University of Verona, Azienda Ospedaliera Universitaria Integrata Verona, AUOI Verona, Piazzale Aristide Stefani 1, 37126, Verona, Italy.
Department of Urology, Rush University Medical Center, Chicago, IL, USA.
Sci Rep. 2024 Apr 15;14(1):8658. doi: 10.1038/s41598-024-59404-w.
The study aimed to evaluate the impact of abdominal drain placement (vs. omission) on perioperative outcomes of robot-assisted partial nephrectomy (RAPN), focusing on complications, time to canalization, deambulation, and pain management. A prospectively-maintained institutional database was queried to get data of patients who underwent RAPN for renal masses between January 2018 and May 2023 at our Institution. Baseline, surgical, and postoperative data were collected. Retrieved patients were stratified based upon placement of abdominal drain (Y/N). Descriptive analyses comparing the two groups were conducted as appropriate.77 After adjusting for potential confounders, a logistic regression analysis was conducted to evaluate significant predictors of any grade and "major" complications. 342 patients were included: 192 patients in the "drain group" versus 150 patients in the "no-drain" group. Renal masses were larger (p < 0.001) and at higher complexity (RENAL score, p = 0.01), in the drain group. Procedures in the drain group had statistically significantly longer operative time, ischemia time, and higher blood loss (all p-values < 0.001). The urinary collecting system was more likely involved compared to the no-drain group (p = 0.01). At multivariate analysis, abdominal drainage was not a significant predictor of any grade (OR 0.79, 95%CI 0.33-1.87) and major postoperative complications (OR 3.62, 95%CI 0.53-9.68). Patients in the drain group experienced a statistically significantly higher hemoglobin drop (p < 0.01). Moreover, they exhibited statistically significant higher paracetamol consumption (p < 0.001) and need for additional opioids (p = 0.02). In summary, the study results suggest the safety of omitting drain placement and remark on the need for personalized decision-making, which considers patient and procedural factors.
这项研究旨在评估在机器人辅助部分肾切除术(RAPN)中放置(vs. 不放置)腹部引流管对围手术期结果的影响,重点关注并发症、置管时间、行走能力和疼痛管理。通过查询我们机构 2018 年 1 月至 2023 年 5 月期间接受 RAPN 治疗的肾肿瘤患者的前瞻性维护机构数据库,获得了数据。收集了基线、手术和术后数据。根据是否放置腹部引流管(Y/N)对检索到的患者进行分层。对两组进行适当的描述性分析。在调整了潜在混杂因素后,进行逻辑回归分析以评估任何等级和“主要”并发症的显著预测因素。共纳入 342 例患者:192 例患者在“引流组”,150 例患者在“无引流组”。引流组的肾脏肿块更大(p<0.001),复杂性更高(RENAL 评分,p=0.01)。引流组的手术时间、缺血时间和失血量均明显较长(所有 p 值均<0.001)。与无引流组相比,引流组更有可能累及尿收集系统(p=0.01)。多变量分析显示,腹部引流不是任何等级(OR 0.79,95%CI 0.33-1.87)和主要术后并发症(OR 3.62,95%CI 0.53-9.68)的显著预测因素。引流组的患者血红蛋白下降幅度明显更大(p<0.01)。此外,他们的扑热息痛消耗量明显更高(p<0.001),需要额外的阿片类药物(p=0.02)。综上所述,研究结果表明不放置引流管是安全的,并强调需要个体化决策,考虑患者和手术因素。