Kashyap Uddip, Saha Sandip K
Department of Mechanical Engineering, Indian Institute of Technology Bombay, Mumbai, 400076 India.
Trans Indian Natl Acad Eng. 2020;5(2):337-341. doi: 10.1007/s41403-020-00101-1. Epub 2020 May 23.
The ongoing global pandemic due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is in the crucial stage. The vaccine is still at the developing stage. Currently, the only way to check the spreading of this virus is self-isolation. It is reported that a good number of health workers are infected while treating patients suffering from COVID 19. Therefore, an effort is made to develop a system that can enhance safety and check unwanted viruses. Although the complete specification of the SARS-CoV-2 is yet to be evaluated, the present work considers the characteristic of SARS-CoV-1, which closely relates to that of SARS-CoV-2. The proteins are one of the most important structural and functional molecules of the virus; therefore, few properties of a protein are considered. In this work, we propose a sanitization procedure of the personal protective equipment (PPE), such as gloves and masks, before and after the use, by employing high voltage charge generator (30 kV) from a very low DC source of 5 V to eliminate the virus from the surface of PPE. The positive output is connected to a metallic surface coated with carbon nanotubes (CNT) or a metallic surface ablated using lithography to achieve desired nano-grooves of 200 nm. At the tip of these nano-grooves, a very high electric field is generated which readily ionises the air in the vicinity of the tip. The high electric field alters the induced dipole of the protein of the virus, causing permanent damage in terms of electroporation. Further positive salt ions diffuse into the protein of the viruses, causing it inactive and disintegrate.
由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引发的全球大流行正处于关键阶段。疫苗仍处于研发阶段。目前，遏制这种病毒传播的唯一方法是自我隔离。据报道，大量医护人员在治疗新冠肺炎患者时被感染。因此，人们努力开发一种能够提高安全性并检测有害病毒的系统。尽管SARS-CoV-2的完整特性尚未得到评估，但目前的工作考虑了与SARS-CoV-2密切相关的SARS-CoV-1的特性。蛋白质是病毒最重要的结构和功能分子之一；因此，本文考虑了蛋白质的一些特性。在这项工作中，我们提出了一种个人防护装备（PPE），如手套和口罩，在使用前后的消毒程序，通过使用来自5V极低直流电源的高压电荷发生器（30kV）来消除PPE表面的病毒。正输出连接到涂有碳纳米管（CNT）的金属表面或使用光刻技术烧蚀的金属表面，以实现所需的200nm纳米凹槽。在这些纳米凹槽的尖端，会产生非常高的电场，该电场很容易使尖端附近的空气电离。高电场改变病毒蛋白质的感应偶极子，在电穿孔方面造成永久性损伤。此外，正盐离子扩散到病毒蛋白质中，使其失活并分解。
