Mehta A B, Tavares De Castro J, San Miguel J F, Yin J A, O'Brien M, Kearney L, Catovsky D
Clin Lab Haematol. 1985;7(2):105-12. doi: 10.1111/j.1365-2257.1985.tb00013.x.
We describe a woman in whom the first manifestation of chronic granulocytic leukaemia (CGL) was an osteolytic lesion. Six months later the peripheral blood showed the picture of CGL in blast crisis. Chromosome studies confirmed the diagnosis and immunological and ultrastructural studies demonstrated the presence of two blast populations: basophil blasts and megakaryoblasts.
我们描述了一位女性，其慢性粒细胞白血病（CGL）的首发表现为溶骨性病变。6个月后，外周血显示处于原始细胞危象的CGL血象。染色体研究确诊了该诊断，免疫和超微结构研究显示存在两种原始细胞群：嗜碱性原始细胞和巨核原始细胞。
