Bluth Thomas, Güldner Andreas, Spieth Peter M
Klinik für Anästhesiologie und Intensivtherapie, Universitätsklinikum Dresden, Fetscherstraße 74, 01307, Dresden, Deutschland.
Anaesthesiologie. 2024 May;73(5):352-362. doi: 10.1007/s00101-024-01407-3.
Extracorporeal membrane oxygenation (ECMO) is often the last resort for escalation of treatment in patients with severe acute respiratory distress syndrome (ARDS). The success of treatment is mainly determined by patient-specific factors, such as age, comorbidities, duration and invasiveness of the pre-existing ventilation treatment as well as the expertise of the treating ECMO center. In particular, the adjustment of mechanical ventilation during ongoing ECMO treatment remains controversial. Although a reduction of invasiveness of mechanical ventilation seems to be reasonable due to physiological considerations, no improvement in outcome has been demonstrated so far for the use of ultraprotective ventilation regimens.
体外膜肺氧合(ECMO)通常是重症急性呼吸窘迫综合征(ARDS)患者治疗升级的最后手段。治疗的成功主要取决于患者的个体因素,如年龄、合并症、既往通气治疗的持续时间和侵入性以及ECMO治疗中心的专业水平。特别是,在进行ECMO治疗期间机械通气的调整仍存在争议。尽管从生理学角度考虑,降低机械通气的侵入性似乎是合理的,但迄今为止,超保护性通气方案的使用并未显示出预后改善。