• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

机器学习在淋巴瘤管理中的应用:当前实践与未来前景

Application of machine learning in the management of lymphoma: Current practice and future prospects.

作者信息

Yuan Junyun, Zhang Ya, Wang Xin

机构信息

Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.

Department of Hematology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China.

出版信息

Digit Health. 2024 Apr 16;10:20552076241247963. doi: 10.1177/20552076241247963. eCollection 2024 Jan-Dec.

DOI:10.1177/20552076241247963
PMID:38628632
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11020711/
Abstract

In the past decade, digitization of medical records and multiomics data analysis in lymphoma has led to the accessibility of high-dimensional records. The digitization of medical records, the visualization of extensive volume data extracted from medical images, and the integration of multiomics methods into clinical decision-making have produced many datasets. As a promising auxiliary tool, machine learning (ML) intends to extract homologous features in large-scale data sets and encode them into various patterns to complete complicated tasks. At present, artificial intelligence and digital mining have shown promising prospects in the field of lymphoma pathological image analysis. The paradigm shift from qualitative analysis to quantitative analysis makes the pathological diagnosis more intelligent and the results more accurate and objective. ML can promote accurate lymphoma diagnosis and provide patients with prognostic information and more individualized treatment options. Based on the above, this comprehensive review of the general workflow of ML highlights recent advances in ML techniques in the diagnosis, treatment, and prognosis of lymphoma, and clarifies the boundedness and future orientation of the ML technique in the clinical practice of lymphoma.

摘要

在过去十年中,淋巴瘤病历的数字化和多组学数据分析使得高维记录变得可获取。病历的数字化、从医学图像中提取的大量数据的可视化以及多组学方法在临床决策中的整合产生了许多数据集。作为一种有前景的辅助工具,机器学习(ML)旨在在大规模数据集中提取同源特征并将其编码为各种模式以完成复杂任务。目前,人工智能和数字挖掘在淋巴瘤病理图像分析领域已展现出有前景的前景。从定性分析到定量分析的范式转变使病理诊断更智能化,结果更准确、客观。ML可促进淋巴瘤的准确诊断,并为患者提供预后信息和更个性化的治疗选择。基于上述内容,这篇对ML一般工作流程的全面综述突出了ML技术在淋巴瘤诊断、治疗和预后方面的最新进展,并阐明了ML技术在淋巴瘤临床实践中的局限性和未来方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1005/11020711/2f4538a686fb/10.1177_20552076241247963-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1005/11020711/1c8e4d13ba10/10.1177_20552076241247963-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1005/11020711/2f4538a686fb/10.1177_20552076241247963-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1005/11020711/1c8e4d13ba10/10.1177_20552076241247963-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1005/11020711/2f4538a686fb/10.1177_20552076241247963-fig3.jpg

相似文献

1
Application of machine learning in the management of lymphoma: Current practice and future prospects.机器学习在淋巴瘤管理中的应用:当前实践与未来前景
Digit Health. 2024 Apr 16;10:20552076241247963. doi: 10.1177/20552076241247963. eCollection 2024 Jan-Dec.
2
Artificial intelligence-aided decision support in paediatrics clinical diagnosis: development and future prospects.人工智能辅助儿科临床诊断决策支持:发展与未来展望。
J Int Med Res. 2020 Sep;48(9):300060520945141. doi: 10.1177/0300060520945141.
3
[Digital Pathology: Current Status and Prospects of Clinical Application].[数字病理学:临床应用的现状与前景]
Sichuan Da Xue Xue Bao Yi Xue Ban. 2021 Mar;52(2):156-161. doi: 10.12182/20210360101.
4
A Machine Learning Tool Using Digital Microscopy (Morphogo) for the Identification of Abnormal Lymphocytes in the Bone Marrow.一种基于数字显微镜的机器学习工具(Morphogo),用于识别骨髓中的异常淋巴细胞。
Acta Cytol. 2021;65(4):354-357. doi: 10.1159/000518382. Epub 2021 Jul 20.
5
Machine Learning and Natural Language Processing in Mental Health: Systematic Review.机器学习和自然语言处理在心理健康中的应用:系统综述。
J Med Internet Res. 2021 May 4;23(5):e15708. doi: 10.2196/15708.
6
Machine learning in oral squamous cell carcinoma: Current status, clinical concerns and prospects for future-A systematic review.机器学习在口腔鳞状细胞癌中的应用:现状、临床关注点及未来展望——系统综述。
Artif Intell Med. 2021 May;115:102060. doi: 10.1016/j.artmed.2021.102060. Epub 2021 Mar 26.
7
Involvement of Machine Learning Tools in Healthcare Decision Making.机器学习工具在医疗保健决策中的应用。
J Healthc Eng. 2021 Jan 27;2021:6679512. doi: 10.1155/2021/6679512. eCollection 2021.
8
Machine Learning in Medical Imaging.医学影像中的机器学习。
J Am Coll Radiol. 2018 Mar;15(3 Pt B):512-520. doi: 10.1016/j.jacr.2017.12.028. Epub 2018 Feb 2.
9
The Application of Artificial Intelligence and Machine Learning in Pituitary Adenomas.人工智能与机器学习在垂体腺瘤中的应用
Front Oncol. 2021 Dec 23;11:784819. doi: 10.3389/fonc.2021.784819. eCollection 2021.
10
Artificial intelligence in anatomical pathology: building a strong foundation for precision medicine.解剖病理学中的人工智能:为精准医学筑牢基础。
Hum Pathol. 2023 Feb;132:31-38. doi: 10.1016/j.humpath.2022.07.008. Epub 2022 Jul 20.

引用本文的文献

1
Recent advances in deep learning for lymphoma segmentation: Clinical applications and challenges.深度学习在淋巴瘤分割方面的最新进展:临床应用与挑战
Digit Health. 2025 Jul 28;11:20552076251362508. doi: 10.1177/20552076251362508. eCollection 2025 Jan-Dec.
2
The Role of Artificial Intelligence and Radiomics in the Management of Lymphomas by PET/CT: The Clairvoyance in Clinic.人工智能和影像组学在淋巴瘤PET/CT管理中的作用:临床中的透视眼
Cancer Manag Res. 2025 Jul 19;17:1457-1475. doi: 10.2147/CMAR.S529589. eCollection 2025.
3
Adoption of artificial intelligence applications in clinical practice: Insights from a Survey of Healthcare Organizations in Lombardy, Italy.

本文引用的文献

1
A machine learning approach to identify groups of patients with hematological malignant disorders.一种机器学习方法,用于识别血液恶性疾病患者群体。
Comput Methods Programs Biomed. 2024 Apr;246:108011. doi: 10.1016/j.cmpb.2024.108011. Epub 2024 Jan 9.
2
Tissue-Matched IgH Gene Rearrangement of Circulating Tumor DNA Shows Significant Value in Predicting the Progression of Diffuse Large B Cell Lymphoma.循环肿瘤DNA的组织匹配IgH基因重排对预测弥漫性大B细胞淋巴瘤进展具有重要价值。
Oncologist. 2024 May 3;29(5):e672-e680. doi: 10.1093/oncolo/oyae008.
3
Diagnosis of chronic B-cell lymphoproliferative disease in peripheral blood = how machine learning may help to the interpretation of flow cytometry data.
意大利伦巴第地区医疗保健组织调查的见解:人工智能应用在临床实践中的采用情况
Digit Health. 2025 Jul 10;11:20552076251355680. doi: 10.1177/20552076251355680. eCollection 2025 Jan-Dec.
4
Diagnostic Implications of NGS-Based Molecular Profiling in Mature B-Cell Lymphomas with Potential Bone Marrow Involvement.基于二代测序的分子谱分析在可能累及骨髓的成熟B细胞淋巴瘤中的诊断意义
Diagnostics (Basel). 2025 Mar 14;15(6):727. doi: 10.3390/diagnostics15060727.
5
Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlook.探索人工智能在化疗研发、癌症诊断和治疗中的作用:当前成就与未来展望。
Front Oncol. 2025 Feb 4;15:1475893. doi: 10.3389/fonc.2025.1475893. eCollection 2025.
6
Applications of Multimodal Artificial Intelligence in Non-Hodgkin Lymphoma B Cells.多模态人工智能在非霍奇金淋巴瘤B细胞中的应用
Biomedicines. 2024 Aug 5;12(8):1753. doi: 10.3390/biomedicines12081753.
7
Hematological Malignancies in Older Patients: Focus on the Potential Role of a Geriatric Assessment Management.老年患者的血液系统恶性肿瘤:聚焦老年评估管理的潜在作用
Diagnostics (Basel). 2024 Jun 29;14(13):1390. doi: 10.3390/diagnostics14131390.
外周血慢性 B 细胞淋巴增殖性疾病的诊断=机器学习如何帮助解释流式细胞术数据。
Hematol Oncol. 2024 Jan;42(1):e3245. doi: 10.1002/hon.3245.
4
A Workflow Combining Machine Learning with Molecular Simulations Uncovers Potential Dual-Target Inhibitors against BTK and JAK3.一种将机器学习与分子模拟相结合的工作流程揭示了针对 BTK 和 JAK3 的潜在双重靶标抑制剂。
Molecules. 2023 Oct 17;28(20):7140. doi: 10.3390/molecules28207140.
5
Machine-learning-based classification of diffuse large B-cell lymphoma patients by a 7-mRNA signature enriched with immune infiltration and cell cycle.基于机器学习的 7 个 mRNA 特征分类弥漫性大 B 细胞淋巴瘤患者,这些特征富含免疫浸润和细胞周期信息。
Clin Transl Oncol. 2024 Apr;26(4):936-950. doi: 10.1007/s12094-023-03326-y. Epub 2023 Oct 3.
6
Can deep learning replace histopathological examinations in the differential diagnosis of cervical lymphadenopathy?深度学习能否替代组织病理学检查用于颈淋巴结病变的鉴别诊断?
Eur Arch Otorhinolaryngol. 2024 Jan;281(1):359-367. doi: 10.1007/s00405-023-08181-9. Epub 2023 Aug 14.
7
Machine Learning Model with Texture Analysis for Automatic Classification of Histopathological Images of Ocular Adnexal Mucosa-associated Lymphoid Tissue Lymphoma of Two Different Origins.基于纹理分析的机器学习模型用于两种不同起源的眼附属器黏膜相关淋巴组织淋巴瘤组织病理学图像的自动分类
Curr Eye Res. 2023 Dec;48(12):1195-1202. doi: 10.1080/02713683.2023.2246696. Epub 2023 Aug 23.
8
Machine Learning Logistic Regression Model for Early Decision Making in Referral of Children with Cervical Lymphadenopathy Suspected of Lymphoma.用于疑似淋巴瘤的儿童颈淋巴结病转诊早期决策的机器学习逻辑回归模型
Cancers (Basel). 2023 Feb 12;15(4):1178. doi: 10.3390/cancers15041178.
9
[F]FDG-PET/CT volumetric parameters can predict outcome in untreated mantle cell lymphoma.[F]氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(FDG-PET/CT)体积参数可预测未经治疗的套细胞淋巴瘤的预后。
Leuk Lymphoma. 2023 Jan;64(1):161-170. doi: 10.1080/10428194.2022.2131415. Epub 2022 Oct 12.
10
Privacy Protection of Healthcare Data over Social Networks Using Machine Learning Algorithms.利用机器学习算法保护社交网络中的医疗保健数据隐私。
Comput Intell Neurosci. 2022 Mar 24;2022:9985933. doi: 10.1155/2022/9985933. eCollection 2022.