Eslaminejad Alireza, Marashian Seyed Mehran, Tajik Jalayeri Mohammad Hadi, Yassari Fatemeh
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Pulmonary Medicine, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Tanaffos. 2023 Feb;22(2):256-261.
The current study aimed to assess some parameters of the cardiopulmonary exercise test (CPET) among end-stage renal disease patients who underwent dialysis. The ultimate goal is to improve disease management to achieve optimal quality of life and exercise capacity in this group of patients.
Through a cross-sectional design, the current study enrolled 46 dialysis patients by simple sampling between Jan 2019 and Jan 2020. Some CPET parameters such as AT, VO, VO/kg, SPO, minute ventilation CO production/O consumption ratios (VE/VCO and VE/VO, respectively), O pulse, heart rate reserve (HRR), breathing reserve (BR) and end-tidal carbon dioxide pressure (PETCO) were focused.
Although a limited sample size, the current study showed that VO/Kg, VE/VCO, PETCO, and SPO are the main parameters affected by dialysis as expected.
The current study suggests using cardiopulmonary rehabilitation for all chronic medical conditions such as chronic kidney disease and end-stage renal disease that increase the rate of metabolic acidosis.
本研究旨在评估接受透析的终末期肾病患者的心肺运动试验（CPET）的一些参数。最终目标是改善疾病管理，以实现该组患者的最佳生活质量和运动能力。
通过横断面设计，本研究在2019年1月至2020年1月期间通过简单抽样招募了46名透析患者。重点关注了一些CPET参数，如无氧阈（AT）、最大摄氧量（VO₂）、每公斤体重最大摄氧量（VO₂/kg）、血氧饱和度（SPO₂）、分钟通气量与二氧化碳产生量/氧气消耗量之比（分别为VE/VCO₂和VE/VO₂）、氧脉搏、心率储备（HRR）、呼吸储备（BR）和呼气末二氧化碳分压（PETCO₂）。
尽管样本量有限，但本研究表明，正如预期的那样，VO₂/kg、VE/VCO₂、PETCO₂和SPO₂是受透析影响的主要参数。
本研究建议对所有会增加代谢性酸中毒发生率的慢性疾病，如慢性肾脏病和终末期肾病，采用心肺康复治疗。
