Correa P, Fontham E, Pickle L W, Chen V, Lin Y P, Haenszel W
J Natl Cancer Inst. 1985 Oct;75(4):645-54.
In south Louisiana, 391 recently diagnosed gastric cancer patients and an equal number of controls were interviewed. Questions asked covered residential and occupational histories, environmental exposures, tobacco use, diet, alcohol consumption, and pertinent demographic characteristics. Elevated relative risks were found for use of tobacco and alcohol products. Diet was found to be the main determinant of gastric cancer risk in south Louisiana. Both dietary patterns and dietary risk factors differed for blacks and whites, although fruits as a group and dietary vitamin C were found to exert strong protective effects for both blacks and whites. Consumption of smoked foods and homemade or home-cured meats increased risk of gastric cancer for blacks but not for whites. The findings are discussed in the light of the prevailing etiologic hypotheses.
在路易斯安那州南部，对391名近期确诊的胃癌患者以及同等数量的对照者进行了访谈。所提问题涵盖居住和职业史、环境暴露情况、烟草使用、饮食、酒精摄入以及相关人口统计学特征。结果发现，烟草和酒精产品的使用会使相对风险升高。研究发现，饮食是路易斯安那州南部胃癌风险的主要决定因素。黑人和白人的饮食模式和饮食风险因素均有所不同，不过水果总体以及饮食中的维生素C对黑人和白人都有很强的保护作用。食用烟熏食品以及自制或家庭腌制肉类会增加黑人患胃癌的风险，但对白人则不然。根据普遍的病因假说对这些研究结果进行了讨论。
