Bendimya Mohammed, Kairouani Mouna, El Magroud Mohammed, Bennani Amal, Al Jarroudi Ouissam, Brahmi Sami Aziz, Afqir Said
Medical Oncology, Faculty of Medicine and Pharmacy of Oujda, Oujda, MAR.
Medical Oncology, Mohammed VI University Hospital, Mohammed First University of Oujda, Oujda, MAR.
Cureus. 2024 Mar 17;16(3):e56333. doi: 10.7759/cureus.56333. eCollection 2024 Mar.
Although gastric cancer is known to be an aggressive tumor that can spread throughout the body, breast metastases are uncommon. This entity is rarely reported in the literature, with an estimated incidence of 0.5 to 1.3%. We report a case of a rare association between a gastric subtype of signet ring cell carcinoma and metastasis to the breast. This uncommon situation is only documented through case reports. Most breast metastases have been detected after diagnosis of primary gastric cancer, during the first year. Several risk factors have been suggested to explain the aggressive behavior of these tumors, which correlates with very poor prognosis and short survival. We report the case of a 22-year-old female patient presenting with widespread metastatic gastric signet ring cell carcinoma with an unusual secondary site in the breast. The diagnosis was confirmed by immunohistochemistry (IHC) and radiology, and the patient was treated with palliative chemotherapy in accordance with the decision of the multidisciplinary tumor board.
尽管胃癌是一种侵袭性肿瘤,可扩散至全身,但乳腺转移并不常见。该实体在文献中鲜有报道,估计发病率为0.5%至1.3%。我们报告一例罕见的印戒细胞癌胃亚型与乳腺转移之间的关联病例。这种罕见情况仅通过病例报告记录。大多数乳腺转移是在原发性胃癌诊断后的第一年内发现的。已经提出了几种风险因素来解释这些肿瘤的侵袭性行为,这与非常差的预后和短生存期相关。我们报告一例22岁女性患者,患有广泛转移的胃印戒细胞癌,乳腺为不寻常的转移部位。通过免疫组织化学(IHC)和放射学确诊,患者根据多学科肿瘤委员会的决定接受了姑息化疗。