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希腊非孕妇人群中分离的生殖支原体的耐药性:过去 15 年的变化趋势。

Antimicrobial resistance of genital mycoplasmas recovered from nonpregnant women in Greece: trends over the last 15 years.

机构信息

Department of Biopathology, Aretaieion University Hospital, Medical School, National & Kapodistrian University of Athens, 76 Vasilisis Sofias Avenue, Athens, 11528, Greece.

Department of Microbiology, Medical School, National & Kapodistrian University of Athens, 75 Mikras Asias Street, Athens, 11527, Greece.

出版信息

Future Microbiol. 2024 Jul 2;19(10):867-875. doi: 10.2217/fmb-2023-0238. Epub 2024 Apr 17.

DOI:10.2217/fmb-2023-0238
PMID:38629933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11290747/
Abstract

To study antimicrobial susceptibilities of genital mycoplasmas recovered from endocervical samples of reproductive-age, nonpregnant women ( = 8,336). For isolation and susceptibility testing, the Mycoplasma IST2 kit was used. As many as 2093 samples were positive for mycoplasmas. The vast majority (>96%) of remained susceptible to tetracycline, doxycycline, josamycin and pristinamycin, whereas susceptibility rates to azithromycin and fluoroquinolones were significantly decreased. exhibited high susceptibility rates to doxycycline, pristinamycin and josamycin (98.1-100%), while susceptibilities to tetracycline and fluoroquinolones were considerably lower. Doxycycline remained highly potent for treating mycoplasmas; nevertheless, susceptibilities to other antimicrobials were significantly diminished.

摘要

研究从生殖年龄、非妊娠妇女的宫颈内样本中分离的生殖道支原体的抗菌药物敏感性(=8336)。用于分离和药敏试验的是支原体 IST2 试剂盒。2093 个样本呈支原体阳性。绝大多数(>96%)仍对四环素、强力霉素、交沙霉素和壮观霉素敏感,而对阿奇霉素和氟喹诺酮类的敏感性显著降低。表现出对强力霉素、壮观霉素和交沙霉素高度敏感(98.1-100%),而对四环素和氟喹诺酮类的敏感性则相当低。强力霉素对治疗支原体仍具有很强的作用;然而,其他抗菌药物的敏感性显著降低。

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本文引用的文献

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Tetracyclines resistance in Mycoplasma and Ureaplasma urogenital isolates derived from human: a systematic review and meta-analysis.支原体和脲原体泌尿生殖道分离株的四环素耐药性:系统评价和荟萃分析。
Ann Clin Microbiol Antimicrob. 2023 Sep 11;22(1):83. doi: 10.1186/s12941-023-00628-5.
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Global analysis on the mutations associated with multidrug-resistant urogenital mycoplasmas and ureaplasmas infection: a systematic review and meta-analysis.全球分析与多药耐药泌尿生殖支原体和脲原体感染相关的突变:系统评价和荟萃分析。
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Prevalence and antibiotics resistance of species and in Hangzhou, China, from 2013 to 2019.2013年至2019年中国杭州[具体物种1]和[具体物种2]的流行情况及抗生素耐药性
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Results from a large cross-sectional study assessing Chlamydia trachomatis, Ureaplasma spp. and Mycoplasma hominis urogenital infections in patients with primary infertility.一项大型横断面研究评估了原发性不孕患者中沙眼衣原体、解脲脲原体和人型支原体泌尿生殖道感染的结果。
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Epidemiological investigation and antimicrobial susceptibility analysis of Ureaplasma and Mycoplasma hominis in a teaching hospital in Shenyang, China.中国沈阳某教学医院解脲脲原体和人型支原体的流行病学调查及药敏分析。
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Should we be testing for urogenital Mycoplasma hominis, Ureaplasma parvum and Ureaplasma urealyticum in men and women? - a position statement from the European STI Guidelines Editorial Board.是否应该在男性和女性中检测泌尿生殖支原体人型、解脲脲原体和脲原体属?——欧洲性传播感染指南编辑委员会的立场声明。
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