新冠大流行各阶段的非致命性自杀行为:在加泰罗尼亚队列中的一项基于人群的研究。

Non-fatal suicide behaviours across phases in the COVID-19 pandemic: a population-based study in a Catalan cohort.

机构信息

Department of Psychiatry, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; Sant Pau Mental Health Research Group, Institut de Recerca Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

Department of Psychiatry, Hospital Juan Ramón Jimenez, Huelva, Spain.

出版信息

Lancet Psychiatry. 2024 May;11(5):348-358. doi: 10.1016/S2215-0366(24)00065-8.

Abstract

BACKGROUND

The COVID-19 pandemic has been extensively discussed in the context of its effect on mental health. Although global suicide rates have remained stable during the pandemic, the specific effect on non-fatal suicide behaviours during and after the pandemic remains underexplored. This study aims to investigate patterns of non-fatal suicide behaviours before, during, and after the pandemic.

METHODS

In this cohort study, we used data from all hospitals in Catalonia, Spain, collected through the Catalan Suicide Risk Code, which is a specifically designed suicide attempt surveillance protocol, involving a face-to-face, in-depth psychiatric evaluation, after a Catalan resident presents any suicide risk behaviour in any public health-care setting. This evaluation centralises data from suicide registries across the territory. We included non-fatal suicide behaviours, meaning suicidal ideation or attempts that did not result in death, and excluded self-harm behaviours not judged to be linked with suicidal ideation. We considered three periods: the pre-confinement period (Jan 1, 2018, to the enforcement of the lockdown in Spain on March 14, 2020); the confinement period (March 14, 2020, to the end of lockdown on June 21, 2020); and the post-confinement period (June 21, 2020, to Dec 31, 2022). We used Bayesian structural time series models to assess the effect of pandemic phases on non-fatal suicide behaviours, and we ran stratified analyses by sex and age to identify distinct patterns among demographic cohorts.

FINDINGS

We obtained 26 482 records from Jan 1, 2018, to Dec 31, 2022. The mean age was 37·94 years (SD 18·07), and the sample included 17 584 (66·4%) women and 8898 (33·6%) men. Data on ethnicity were not collected. Temporal trends showed a mild increase in non-fatal suicide behaviours from Jan 1, 2018, to March 13, 2020; a reduction during the confinement period; and a subsequent rise after confinement. Bayesian models suggested a significant causal effect of lockdown easing, resulting in a 50·77% increase in non-fatal suicide behaviours (95% credible interval [CrI] 26·62-76·58; p<0·0001). Stratified analyses indicated that the easing of lockdown resulted in a significant increase in non-fatal suicide behaviours among women (25·92%; 6·71-44·72; p=0·011) and among individuals aged 18 years and younger (72·75%; 38·81-108·11; p<0·0001).

INTERPRETATION

This study provides a comprehensive examination of non-fatal suicide behaviours in Catalonia, Spain, emphasising the dynamics of different COVID-19 pandemic phases. The initial reduction during strict lockdown aligns with Joiner's Interpersonal Theory of Suicide, whereas the post-confinement rise reflects complex factors, including social isolation and economic challenges. Sex-specific and age-specific analyses underscore distinct vulnerabilities, emphasising the need for targeted preventive strategies.

FUNDING

Centro de Investigación Biomédica en Red de Salud Mental annual budget of G21, Agència de Gestió d'Ajuts Universitaris i de Recerca of the Generalitat de Catalunya.

TRANSLATIONS

For the Catalan and Spanish translations of the abstract see Supplementary Materials section.

摘要

背景

COVID-19 大流行对心理健康的影响受到了广泛的讨论。尽管全球自杀率在大流行期间保持稳定,但大流行期间和之后非致命性自杀行为的具体影响仍未得到充分探索。本研究旨在调查大流行前后非致命性自杀行为的模式。

方法

在这项队列研究中,我们使用了来自西班牙加泰罗尼亚所有医院的数据,这些数据是通过加泰罗尼亚自杀风险代码收集的,这是一种专门设计的自杀未遂监测方案,涉及到在加泰罗尼亚居民在任何公共医疗保健环境中出现任何自杀风险行为后,进行面对面的深入精神评估。该评估集中了整个领土内自杀登记处的数据。我们纳入了非致命性自杀行为,即没有导致死亡的自杀意念或企图,并排除了被认为与自杀意念无关的自我伤害行为。我们考虑了三个时期:禁闭前时期(2018 年 1 月 1 日至 2020 年 3 月 14 日西班牙实施封锁期间);禁闭期间(2020 年 3 月 14 日至 2020 年 6 月 21 日封锁结束期间);和禁闭后时期(2020 年 6 月 21 日至 2022 年 12 月 31 日)。我们使用贝叶斯结构时间序列模型来评估大流行阶段对非致命性自杀行为的影响,并按性别和年龄进行分层分析,以确定不同人口群体中的独特模式。

发现

我们从 2018 年 1 月 1 日至 2022 年 12 月 31 日获得了 26482 条记录。平均年龄为 37.94 岁(标准差 18.07),样本包括 17584 名(66.4%)女性和 8898 名(33.6%)男性。种族数据未收集。时间趋势显示,非致命性自杀行为从 2018 年 1 月 1 日至 2020 年 3 月 13 日略有增加;在禁闭期间减少;并在禁闭后再次上升。贝叶斯模型表明,封锁放松具有显著的因果效应,导致非致命性自杀行为增加 50.77%(95%可信区间 26.62-76.58;p<0.0001)。分层分析表明,封锁放松导致女性(25.92%;6.71-44.72;p=0.011)和 18 岁及以下人群(72.75%;38.81-108.11;p<0.0001)非致命性自杀行为显著增加。

解释

本研究对西班牙加泰罗尼亚的非致命性自杀行为进行了全面考察,强调了不同 COVID-19 大流行阶段的动态。严格封锁期间的最初减少符合乔伊纳的人际理论自杀,而禁闭后的上升反映了复杂的因素,包括社会隔离和经济挑战。性别和年龄的特定分析强调了不同的脆弱性,强调了需要有针对性的预防策略。

资金

Centro de Investigación Biomédica en Red de Salud Mental 的年度预算为 G21,Agència de Gestió d'Ajuts Universitaris i de Recerca de la Generalitat de Catalunya。

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