Shangyu people's Hospital, Shaoxing City, Zhejiang Province, 312300, China.
Run Run Shaw Hospital, Zhejiang University, Hangzhou City, Zhejiang Province, China.
BMC Oral Health. 2024 Apr 17;24(1):466. doi: 10.1186/s12903-024-04141-9.
To investigate the association of leisure-time physical activity and serum cotinine levels with the risk of periodontitis in the general population and to further analyze the interaction between leisure-time physical activity and serum cotinine levels on the risk of periodontitis.
This was a cross-sectional study, extracting data from 9605 (56.19%) participants in the National Health and Nutrition Examination Survey (NHANES) database from 2009 to 2014, and analyzing the relationship and interaction effects of serum cotinine level, leisure time physical activity, and risk of periodontitis by weighted univariate logistic modeling; Effect sizes were determined using ratio of ratios (OR), 95% confidence intervals (95% CI).
5,397 (56.19%) of 9,605 participants had periodontitis; an increased risk of periodontitis was found in those in the leisure time physical activity intensity < 750 MET × min/week group (OR = 1.44, 95% CI: 1.17-1.78). Serum cotinine levels ≥ 0.05 ng/ml were associated with an increased risk of periodontitis (OR = 1.99, 95% CI: 1.69-2.33). The group with low leisure physical activity and serum cotinine levels ≥ 0.05 ng/ml had an increased risk of periodontitis compared to the group with high leisure physical activity and serum cotinine levels < 0.05 ng/ml (OR = 2.48, 95% CI: 1.88-3.27). Interaction metrics RERI = 0.90 (95% CI: 0.44-1.36) and API = 0.36 (95% CI: 0.18-0.55); CI for SI = 2.55 (95% CI: 1.03-6.28). for API 0.36.
Leisure time physical activity intensity interacted with smoking exposure on periodontitis risk and may provide the general population with the opportunity to Increasing leisure-time physical activity and smoking cessation may provide recommendations for the general population.
研究休闲时间体力活动和血清可替宁水平与普通人群牙周炎风险的关系，并进一步分析休闲时间体力活动与血清可替宁水平对牙周炎风险的交互作用。
这是一项横断面研究，从 2009 年至 2014 年的国家健康与营养调查（NHANES）数据库中提取了 9605 名（56.19%）参与者的数据，通过加权单变量逻辑建模分析血清可替宁水平、休闲时间体力活动与牙周炎风险的关系和交互作用；使用比值比（OR）和 95%置信区间（95%CI）确定效应大小。
9605 名参与者中，5397 名（56.19%）患有牙周炎；与休闲时间体力活动强度<750MET×min/周组相比，休闲时间体力活动强度增加的参与者患牙周炎的风险增加（OR=1.44，95%CI：1.17-1.78）。血清可替宁水平≥0.05ng/ml 与牙周炎风险增加相关（OR=1.99，95%CI：1.69-2.33）。与高休闲体力活动和血清可替宁水平<0.05ng/ml 相比，低休闲体力活动和血清可替宁水平≥0.05ng/ml 的组患牙周炎的风险增加（OR=2.48，95%CI：1.88-3.27）。交互度量 RERI=0.90（95%CI：0.44-1.36）和 API=0.36（95%CI：0.18-0.55）；SI 的 CI 为 2.55（95%CI：1.03-6.28）。API 为 0.36。
休闲时间体力活动强度与吸烟暴露对牙周炎风险存在交互作用，可能为普通人群提供增加休闲时间体力活动和戒烟的机会，为普通人群提供建议。
