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艾滋病毒与新冠病毒合并感染:本地视角

HIV and SARS-Cov-2 Co-Infection: A Local Perspective.

作者信息

Bilek Heval Can, Deveci Aydın

机构信息

Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayıs University School of Medicine, Samsun, Turkey.

出版信息

Infect Dis Clin Microbiol. 2022 Jun 13;4(2):122-128. doi: 10.36519/idcm.2022.131. eCollection 2022 Jun.

Abstract

OBJECTIVE

As the Coronavirus disease 2019 (COVID-19) pandemic spread globally, more human immunodeficiency virus (HIV) positive patients began to appear infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We aimed to evaluate the clinical course of HIV and SARS-CoV-2 co-infected patients from a local perspective.

METHODS

HIV and SARS-CoV-2 co-infected patients diagnosed between March 2020 to June 2021 at a tertiary hospital in Turkey were analyzed retrospectively.

RESULTS

Thirty HIV and SARS-CoV-2 co-infected patients were included. Five patients were female, 25 were male, and the mean age was 44.5 ±10.2 years. Twenty-three (76.7%) patients were known to be HIV-positive before their admission to the hospital, and seven (23.7%) patients, were detected by screening after the diagnosis of COVID-19. All patients were known to be HIV-positive; they were on antiretroviral therapy (ART) and virologically suppressed. Twenty-seven patients had a mild course. Three patients were hospitalized, and of them, two patients had died. All hospitalized patients were male and were ART-naïve.

CONCLUSION

HIV infection alone did not increase the severity of the course of COVID-19 and did not increase the mortality in COVID-19.

摘要

目的

随着2019年冠状病毒病(COVID-19)大流行在全球蔓延,越来越多的人类免疫缺陷病毒(HIV)阳性患者开始出现感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的情况。我们旨在从本地视角评估HIV与SARS-CoV-2合并感染患者的临床病程。

方法

对2020年3月至2021年6月期间在土耳其一家三级医院诊断出的HIV与SARS-CoV-2合并感染患者进行回顾性分析。

结果

纳入了30例HIV与SARS-CoV-2合并感染患者。其中5例为女性,25例为男性,平均年龄为44.5±10.2岁。23例(76.7%)患者在入院前已知为HIV阳性,7例(23.7%)患者在COVID-19诊断后通过筛查检测出。所有患者均已知为HIV阳性;他们正在接受抗逆转录病毒治疗(ART)且病毒学得到抑制。27例患者病程较轻。3例患者住院,其中2例死亡。所有住院患者均为男性且未接受过ART治疗。

结论

单纯HIV感染不会增加COVID-19病程的严重程度,也不会增加COVID-19的死亡率。

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