Bilek Heval Can, Deveci Aydın
Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayıs University School of Medicine, Samsun, Turkey.
Infect Dis Clin Microbiol. 2022 Jun 13;4(2):122-128. doi: 10.36519/idcm.2022.131. eCollection 2022 Jun.
As the Coronavirus disease 2019 (COVID-19) pandemic spread globally, more human immunodeficiency virus (HIV) positive patients began to appear infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We aimed to evaluate the clinical course of HIV and SARS-CoV-2 co-infected patients from a local perspective.
HIV and SARS-CoV-2 co-infected patients diagnosed between March 2020 to June 2021 at a tertiary hospital in Turkey were analyzed retrospectively.
Thirty HIV and SARS-CoV-2 co-infected patients were included. Five patients were female, 25 were male, and the mean age was 44.5 ±10.2 years. Twenty-three (76.7%) patients were known to be HIV-positive before their admission to the hospital, and seven (23.7%) patients, were detected by screening after the diagnosis of COVID-19. All patients were known to be HIV-positive; they were on antiretroviral therapy (ART) and virologically suppressed. Twenty-seven patients had a mild course. Three patients were hospitalized, and of them, two patients had died. All hospitalized patients were male and were ART-naïve.
HIV infection alone did not increase the severity of the course of COVID-19 and did not increase the mortality in COVID-19.
随着2019年冠状病毒病(COVID-19)大流行在全球蔓延,越来越多的人类免疫缺陷病毒(HIV)阳性患者开始出现感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的情况。我们旨在从本地视角评估HIV与SARS-CoV-2合并感染患者的临床病程。
对2020年3月至2021年6月期间在土耳其一家三级医院诊断出的HIV与SARS-CoV-2合并感染患者进行回顾性分析。
纳入了30例HIV与SARS-CoV-2合并感染患者。其中5例为女性,25例为男性,平均年龄为44.5±10.2岁。23例(76.7%)患者在入院前已知为HIV阳性,7例(23.7%)患者在COVID-19诊断后通过筛查检测出。所有患者均已知为HIV阳性;他们正在接受抗逆转录病毒治疗(ART)且病毒学得到抑制。27例患者病程较轻。3例患者住院,其中2例死亡。所有住院患者均为男性且未接受过ART治疗。
单纯HIV感染不会增加COVID-19病程的严重程度,也不会增加COVID-19的死亡率。