Pınarlık Fatihan, Keske Şiran, Rozanes İzzet, Ergönül Önder
Graduate School of Health Sciences, Koç University, İstanbul, Turkey.
Koç University Isbank Center for Infectious Diseases, Koç University Hospital, İstanbul, Turkey.
Infect Dis Clin Microbiol. 2023 Mar 11;5(1):49-52. doi: 10.36519/idcm.2023.197. eCollection 2023 Mar.
A 57-year-old female patient presented with fever, nausea, vomiting, loss of appetite, and weight loss within the last two months. Ceftriaxone and metronidazole therapy was started upon discovery of a liver abscess but provided no benefit. Following the of abscess biopsy, the patient developed fever, itching, anemia, acute renal failure, hyperbilirubinemia, and eosinophilia that required intensive care unit (ICU) admission. The antibodies were detected by enzyme-linked immunosorbent assay (ELISA). Triclabendazole was started, after which the symptoms and magnetic resonance imaging (MRI) findings regressed. Even without eosinophilia, should be considered in cases with a liver abscess that does not respond to antibiotics.
一名57岁女性患者在过去两个月内出现发热、恶心、呕吐、食欲不振和体重减轻。发现肝脓肿后开始使用头孢曲松和甲硝唑治疗，但未见疗效。脓肿活检后，患者出现发热、瘙痒、贫血、急性肾衰竭、高胆红素血症和嗜酸性粒细胞增多，需要入住重症监护病房（ICU）。通过酶联免疫吸附测定（ELISA）检测抗体。开始使用三氯苯达唑治疗后，症状和磁共振成像（MRI）结果有所改善。即使没有嗜酸性粒细胞增多，对于对抗生素无反应的肝脓肿病例，也应考虑（某种情况，原文此处不完整）。
