Aksoy D Y, Kerimoglu U, Oto A, Erguven S, Arslan S, Unal S, Batman F, Bayraktar Y
Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey.
Clin Microbiol Infect. 2005 Nov;11(11):859-61. doi: 10.1111/j.1469-0691.2005.01254.x.
Fascioliasis, caused by the liver fluke Fasciola hepatica, is an infection that occurs worldwide, although humans are accidental hosts. F. hepatica infection comprises two stages, hepatic and biliary, with different signs and symptoms. Stool examination and ELISA can be used for the initial diagnosis. Radiographic techniques, such as computerised tomography and ultrasonography, as well as magnetic resonance imaging, are used widely for confirmation and follow-up of the disease. Invasive techniques, such as percutaneous cholangiography, endoscopic retrograde cholangiography and liver biopsy, may aid in the diagnosis but are not essential. Triclabendazole is recommended as the first-line agent for the treatment of F. hepatica infection, with bithionol as an alternative.
肝片吸虫病由肝片形吸虫（Fasciola hepatica）引起，尽管人类是偶然宿主，但这种感染在全球范围内都有发生。肝片形吸虫感染包括肝期和胆管期两个阶段，有不同的体征和症状。粪便检查和酶联免疫吸附测定（ELISA）可用于初步诊断。放射学技术，如计算机断层扫描和超声检查，以及磁共振成像，被广泛用于疾病的确诊和随访。侵入性技术，如经皮胆管造影、内镜逆行胆管造影和肝活检，可能有助于诊断，但并非必不可少。三氯苯达唑被推荐作为治疗肝片形吸虫感染的一线药物，硫双二氯酚可作为替代药物。
