Pulkkinen P
Ann Chir Gynaecol Suppl. 1985;197:55-9.
In this multivariate prospective case controlled study a total of 576 pregnancies were examined. Of the mothers 162 were light, 46 moderate and 80 ex-smokers, and 288 non-smokers. Forty variants of the mother, pregnancy, delivery and the newborn were taken in consideration. The mean gestational age in all study groups varied between 276-280 days, the maternal gestational weight gain between 12.2-14.7 kg. No difference was observed in maternal pre-pregnant weight and height. Light smokers' newborns' mean birth weight was 3396 g, moderate smokers' 3196, ex-smokers' 3516, and non smoking controls' 3577. When maternal size, gestational age and weight gain were standardised, smoking remained the only cause to explain the differences observed between smokers' and non-smokers' newborns' characteristics. No differences were observed between ex-smokers, women who stopped smoking during the first trimester of gestation, and non smoking controls.
在这项多变量前瞻性病例对照研究中，共检查了576例妊娠情况。母亲中，162例为轻度吸烟者，46例为中度吸烟者，80例为既往吸烟者，288例为非吸烟者。考虑了母亲、妊娠、分娩和新生儿的40个变量。所有研究组的平均孕周在276 - 280天之间，母亲孕期体重增加在12.2 - 14.7千克之间。孕前母亲的体重和身高未观察到差异。轻度吸烟者的新生儿平均出生体重为3396克，中度吸烟者的为3196克，既往吸烟者的为3516克，非吸烟对照组的为3577克。当对母亲的体型、孕周和体重增加进行标准化后，吸烟仍然是解释吸烟者和非吸烟者新生儿特征差异的唯一原因。在既往吸烟者、妊娠头三个月戒烟的女性和非吸烟对照组之间未观察到差异。
