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组织相容性抗原与宫内胎儿生长受限

Histocompatibility antigens and intrauterine fetal growth retardation.

作者信息

Weir P E, Oats J N, Holdsworth R, Cross R

出版信息

Aust N Z J Obstet Gynaecol. 1985 May;25(2):108-10. doi: 10.1111/j.1479-828x.1985.tb00619.x.

DOI:10.1111/j.1479-828x.1985.tb00619.x
PMID:3863585
Abstract

Maternal-fetal antigen compatibility adversely affects fetal and placental weights in animal experiments and is associated with recurrent spontaneous abortion and preeclampsia in human reproduction. HLA A and B types of the mother, father and infant were determined in 30 pregnancies complicated by intrauterine fetal growth retardation (IUGR) and in 32 normal pregnancies. The frequency and degree of antigenic compatibility between the parents and the mothers and their infants were compared between the groups. There was no evidence that IUGR was associated with a significant degree of HLA A and B antigenic compatibility.

摘要

母胎抗原相容性在动物实验中对胎儿和胎盘重量产生不利影响,在人类生殖中与复发性自然流产和先兆子痫相关。对30例并发宫内胎儿生长受限(IUGR)的妊娠和32例正常妊娠测定了母亲、父亲和婴儿的HLA A和B型。比较了两组中父母之间以及母亲与婴儿之间抗原相容性的频率和程度。没有证据表明IUGR与显著程度的HLA A和B抗原相容性相关。

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