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肿瘤大小并非一切:推进肿瘤放射组学作为肿瘤药物研发和临床护理的精准医学生物标志物。RESCIST 工作组协调的多学科研讨会报告。

Tumor Size Is Not Everything: Advancing Radiomics as a Precision Medicine Biomarker in Oncology Drug Development and Clinical Care. A Report of a Multidisciplinary Workshop Coordinated by the RECIST Working Group.

机构信息

AstraZeneca, Gaithersburg, MD.

Queen's University, Kingston, ON, Canada.

出版信息

JCO Precis Oncol. 2024 Apr;8:e2300687. doi: 10.1200/PO.23.00687.

Abstract

Radiomics, the science of extracting quantifiable data from routine medical images, is a powerful tool that has many potential applications in oncology. The Response Evaluation Criteria in Solid Tumors Working Group (RWG) held a workshop in May 2022, which brought together various stakeholders to discuss the potential role of radiomics in oncology drug development and clinical trials, particularly with respect to response assessment. This article summarizes the results of that workshop, reviewing radiomics for the practicing oncologist and highlighting the work that needs to be done to move forward the incorporation of radiomics into clinical trials.

摘要

放射组学是一门从常规医学图像中提取可量化数据的科学,它是一种强大的工具,在肿瘤学中有许多潜在的应用。实体瘤反应评估标准工作组(Response Evaluation Criteria in Solid Tumors Working Group,RWG)于 2022 年 5 月举办了一次研讨会,汇集了各方利益相关者,讨论放射组学在肿瘤药物开发和临床试验中的潜在作用,特别是在反应评估方面。本文总结了该研讨会的结果,为肿瘤学临床医生综述了放射组学,并强调了为将放射组学纳入临床试验而需要开展的工作。

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