Pathology and Clinical Governance, Australian Red Cross Lifeblood, Brisbane, QLD, Australia.
Strategy and Growth, Australian Red Cross Lifeblood, Melbourne, VIC, Australia.
Int J Equity Health. 2024 Apr 18;23(1):77. doi: 10.1186/s12939-024-02170-y.
Blood collection agencies are integrating precision medicine techniques to improve and individualise blood donor and recipient outcomes. These organisations have a role to play in ensuring equitable application of precision medicine technologies for both donors and transfusion recipients. BODY: Precision medicine techniques, including molecular genetic testing and next generation sequencing, have been integrated in transfusion services to improve blood typing and matching with the aim to reduce a variety of known transfusion complications. Internationally, priorities in transfusion research have aimed to optimise services through the use of precision medicine technologies and consider alternative uses of genomic information to personalise transfusion experiences for both recipients and donors. This has included focusing on the use of genomics when matching blood products for transfusion recipients, to personalise a blood donor's donation type or frequency, and longitudinal donor research utilising blood donor biobanks.
Equity in precision services and research must be of highest importance for blood collection agencies to maintain public trust, especially when these organisations rely on volunteer donors to provide transfusion services. The investment in implementing equitable precision medicine services, including development of blood donor biobanks, has the potential to optimise and personalise services for both blood donors and transfusion recipients.
血液采集机构正在整合精准医学技术,以改善和个性化献血者和受血者的结果。这些组织在确保公平应用精准医学技术方面,为献血者和输血受血者都发挥着作用。
精准医学技术,包括分子遗传学检测和下一代测序,已被整合到输血服务中,以改善血型鉴定和配型,旨在减少各种已知的输血并发症。在国际上,输血研究的重点是通过使用精准医学技术优化服务,并考虑基因组信息的替代用途,为受血者和献血者个性化输血体验。这包括在为输血受血者匹配血液制品时关注基因组学,以个性化献血者的献血类型或频率,以及利用献血者生物库进行纵向献血者研究。
对于血液采集机构来说,精准服务和研究的公平性必须是最重要的,以维护公众的信任,特别是当这些组织依赖志愿者献血者提供输血服务时。投资实施公平的精准医学服务,包括建立献血者生物库,有可能优化和个性化献血者和输血受血者的服务。