Moshirfar Majid, Kelkar Neil, Ronquillo Yasmyne C, Hoopes Phillip C
Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA.
John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT, USA.
Case Rep Ophthalmol. 2024 Apr 18;15(1):374-382. doi: 10.1159/000533579. eCollection 2024 Jan-Dec.
Duchenne muscular dystrophy (DMD) is an X-linked disorder due to a dystrophin mutation and is the leading cause of muscular dystrophy. DMD presents with characteristic systemic effects, including severe muscular atrophy, cardiomyopathy, and ocular manifestations. Performing corneal refractive surgeries in patients with DMD raises concerns regarding patient positioning, risk of cataracts, and other comorbid conditions. Published reports of photorefractive keratectomy, laser-assisted in situ keratomileuses, and small incision lenticule extraction are lacking in this population. Here, we discuss a patient being evaluated for a corneal refractive surgery. This article also discusses the current understanding of DMD, known ocular manifestations, and factors to consider when evaluating a patient for potential corrective vision laser surgery.
杜氏肌营养不良症(DMD)是一种由于肌营养不良蛋白突变导致的X连锁疾病,是肌营养不良的主要原因。DMD具有特征性的全身影响,包括严重的肌肉萎缩、心肌病和眼部表现。对DMD患者进行角膜屈光手术引发了对患者体位、白内障风险和其他合并症的担忧。目前尚无关于该人群的准分子激光角膜切削术、准分子原位角膜磨镶术和小切口基质透镜切除术的报道。在此,我们讨论一名正在接受角膜屈光手术评估的患者。本文还讨论了对DMD的当前认识、已知的眼部表现以及在评估患者是否适合进行潜在的矫正视力激光手术时需要考虑的因素。