Zimmerman M, Coryell W, Pfohl B
Psychiatry Res. 1985 Sep;16(1):37-43. doi: 10.1016/0165-1781(85)90026-5.
Because melancholic subtyping is associated with pretreatment symptom severity, the type of data-analytic technique used in examining treatment validity may affect one's conclusions. We examined the relationship between the presence or absence of melancholia and the response to electroconvulsive therapy (ECT) in 87 depressed inpatients. Depending on the definition of improvement used, melancholic subtyping was either not associated with ECT response, or non-melancholics had a better outcome than melancholics. We suggest that standard methods of outcome evaluation be required in therapy outcome studies.
由于忧郁症亚型与治疗前症状严重程度相关，用于检验治疗有效性的数据分析技术类型可能会影响一个人的结论。我们研究了87名抑郁症住院患者中忧郁症的有无与电休克治疗（ECT）反应之间的关系。根据所使用的改善定义，忧郁症亚型与ECT反应要么无关，要么非忧郁症患者的治疗结果比忧郁症患者更好。我们建议在治疗结果研究中需要采用标准的结果评估方法。
