Emerging Diseases Epidemiology Unit, Institut Pasteur, Université Paris Cité, Paris, France; Sorbonne Université, Ecole Doctorale Pierre Louis de Santé Publique, Paris, France.
Université Paris Cité, LIRAES F-75006, Paris, France.
Vaccine. 2024 May 22;42(14):3288-3299. doi: 10.1016/j.vaccine.2024.04.024. Epub 2024 Apr 19.
Widely documented psychological antecedents of vaccination are confidence in vaccines, complacency, convenience, calculation, collective responsibility (5C model) with the recent addition of confidence in the wider system and social conformism. While the capacity of these seven antecedents (7C) to explain variance in COVID-19 vaccine intentions has been previously documented, we study whether these factors also are associated with vaccine behaviours, beyond intentions.
From February to June 2022, we recruited a sample of adults in France, including persons with notified recent SARS-CoV-2 infection, along with relatives and randomly selected non-infected persons. Participants completed self-administered questionnaires assessing COVID-19 vaccination history and the 7C antecedents. We defined vaccination behaviours as three outcomes: at-least-one-dose vaccine status by 2022 (N = 49,019), up-to-date vaccination status (N = 46,566), and uptake speed of first dose (N = 25,998). We conducted multivariable logistic regressions and Cox models.
Among the 49,019 participants, 95.0% reported receipt of at least one dose and 89.8% were up to date with recommendations. All 7C antecedents were significantly associated with the outcomes, although effects were weaker for up-to-date vaccination status and uptake speed. The strongest effects (most vs. least vaccine-favourable attitude level, at-least-one-dose vaccination status) were observed for collective responsibility (OR: 14.44; 95%CI: 10.72-19.45), calculation (OR: 10.29; 95%CI: 7.53-14.05), and confidence in the wider system (OR: 8.94; 95%CI: 6.51-12.27).
This study demonstrates that the 7C not only explain vaccine intention, but also vaccine behaviours, and underpins the importance of developing vaccine promotion strategies considering the 7C antecedents.
广泛记录的疫苗接种心理前因包括对疫苗的信心、自满、便利、计算、集体责任感(5C 模型),最近又增加了对更广泛系统的信心和社会从众。尽管这七个前因(7C)已经被证明可以解释 COVID-19 疫苗接种意愿的差异,但我们研究了这些因素是否也与疫苗接种行为有关,而不仅仅是意图。
2022 年 2 月至 6 月,我们在法国招募了一组成年人样本,包括最近通知的 SARS-CoV-2 感染患者,以及他们的亲属和随机选择的未感染人员。参与者完成了自我管理的问卷调查,评估了 COVID-19 疫苗接种史和 7C 前因。我们将疫苗接种行为定义为三个结果:2022 年至少接种一剂疫苗的状态(N=49019)、最新接种状态(N=46566)和第一剂接种速度(N=25998)。我们进行了多变量逻辑回归和 Cox 模型分析。
在 49019 名参与者中,95.0%报告至少接种了一剂疫苗,89.8%符合建议的最新接种状态。所有 7C 前因与结果均显著相关,尽管对最新接种状态和接种速度的影响较弱。最强的影响(最有利于疫苗接种态度水平与最不利于疫苗接种态度水平相比,至少接种一剂疫苗的状态)观察到的是集体责任感(OR:14.44;95%CI:10.72-19.45)、计算(OR:10.29;95%CI:7.53-14.05)和对更广泛系统的信心(OR:8.94;95%CI:6.51-12.27)。
这项研究表明,7C 不仅可以解释疫苗接种意愿,还可以解释疫苗接种行为,并且支持了在制定疫苗推广策略时考虑 7C 前因的重要性。