Wysenbeek A J, Mor F, Lurie Y, Weinberger A
Ann Rheum Dis. 1985 Nov;44(11):752-3. doi: 10.1136/ard.44.11.752.
Twenty fibrositic patients were treated with imipramine 50-75 mg/day. Only two patients responded favourably. Nineteen patients stopped therapy during the initial three-month period: 14 of them due to lack of response, while two of these concomitantly disclosed side effects. The additional five patients stopped therapy mainly due to side effects, while only one of them improved with therapy. One patient, only, improved and adhered to therapy for more than three months.
20名纤维化患者接受了每天50 - 75毫克丙咪嗪的治疗。只有两名患者反应良好。19名患者在最初的三个月内停止了治疗：其中14名是因为没有反应，其中两名同时出现了副作用。另外5名患者主要因副作用停止治疗，而其中只有1名患者在治疗后有所改善。只有1名患者有所改善并坚持治疗超过了三个月。
