老挝乙肝疫苗接种的相关因素:2011/12年和2017年多指标类集调查结果

Factors associated with hepatitis B vaccination in Laos: findings from the multiple indicator cluster surveys in 2011/12 and 2017.

作者信息

Dekker Trude, Hefele Lisa, Neven Anouk, Hübschen Judith M, Essink Dirk R, Black Antony P

机构信息

Athena Institute, Faculty of Science, Vrije Universiteit, Amsterdam, Netherlands.

Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.

出版信息

Lancet Reg Health West Pac. 2024 Apr 15;46:101059. doi: 10.1016/j.lanwpc.2024.101059. eCollection 2024 May.

Abstract

BACKGROUND

Within Laos, the vaccination coverage rates with the monovalent hepatitis B birth dose vaccine and hepatitis B antigen-containing combination vaccines remain stagnant with 75% and 64%, respectively, in 2021. In this study, we used data from the Multiple Indicator Cluster Surveys to identify possible factors that represent barriers for receiving these childhood vaccinations.

METHODS

Data from the Multiple Indicator Cluster Surveys in 2011/12 and 2017 were analysed to examine factors associated with receiving the hepatitis B-containing vaccines using regression modelling. Data analyses were conducted in R.

FINDINGS

In 2011/12, the weight-adjusted coverage rate for receiving the hepatitis B birth dose was 48%, while the coverage with the hepatitis B antigen-containing combination vaccine was 55.1% based on both vaccination documents and recall; compared to 69.3% and 59.4% respectively in 2017. Ethno-linguistic group, maternal education, healthcare utilization and wealth were associated with receiving the vaccinations against hepatitis B.

INTERPRETATION

National estimates of vaccination coverage rates can conceal country-specific regional or socio-economic variations. Children from Hmong-Mien households, from less wealthier households and whose mothers were less educated and were not able to or did not utilize healthcare were identified as being less likely to receive the vaccinations. These findings indicate the need for improving access to healthcare, in particular for minority groups.

FUNDING

This work was supported by the Ministry of Foreign and European Affairs, Luxembourg and the Luxembourg Institute of Health (project "Luxembourg-Laos Partnership for Research and Capacity Building in Infectious Disease Surveillance").

摘要

背景

在老挝,单价乙肝出生剂量疫苗和含乙肝抗原的联合疫苗的接种覆盖率停滞不前,2021年分别为75%和64%。在本研究中,我们使用多指标类集调查的数据来确定可能代表儿童接种这些疫苗障碍的因素。

方法

分析2011/12年和2017年多指标类集调查的数据,使用回归模型检查与接种含乙肝疫苗相关的因素。数据分析在R软件中进行。

结果

在2011/12年,根据接种记录和回忆,乙肝出生剂量的体重调整接种覆盖率为48%,而含乙肝抗原联合疫苗的接种覆盖率为55.1%;相比之下,2017年分别为69.3%和59.4%。民族语言群体、母亲教育程度、医疗保健利用情况和财富与乙肝疫苗接种相关。

解读

全国疫苗接种覆盖率估计可能掩盖特定国家的地区或社会经济差异。来自苗族-瑶族家庭、较贫困家庭、母亲受教育程度较低且无法或未利用医疗保健的儿童被确定为接种疫苗的可能性较小。这些发现表明需要改善医疗保健的可及性,特别是对少数群体。

资金

这项工作得到了卢森堡外交与欧洲事务部和卢森堡健康研究所(项目“卢森堡-老挝传染病监测研究与能力建设伙伴关系”)的支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d432/11033145/39b01c7f060d/gr1.jpg

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