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结节病相关性中间葡萄膜炎继发的血管增生性肿瘤

Vasoproliferative Tumor Secondary to Sarcoidosis-Associated Intermediate Uveitis.

作者信息

Jalil Sara Abdel, Jaouni Tareq, Amer Radgonde

机构信息

Hadassah Medical Center, Department of Ophthalmology, Jerusalem, Israel.

出版信息

Turk J Ophthalmol. 2024 Apr 19;54(2):108-111. doi: 10.4274/tjo.galenos.2024.36926.

DOI:10.4274/tjo.galenos.2024.36926
PMID:38645965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11034545/
Abstract

We report the visual and clinical outcomes of a middle-aged woman who presented with exudative retinal detachment (ERD) secondary to a vasoproliferative tumor (VPT) in an eye with sarcoidosis-associated intermediate uveitis. A 55-year-old woman previously diagnosed with sarcoidosis presented with decreased vision in the left eye (LE). Visual acuity in the LE was counting fingers. She had active vitritis, and a peripheral retinal vascular mass was noted in the superotemporal periphery. The mass was associated with ERD involving the posterior pole. The patient was managed with systemic and intravitreal steroids, and cyclosporine was subsequently added as a steroid-sparing agent. Because of recurrence of ERD, the patient underwent pars plana vitrectomy, and cryotherapy and laser photocoagulation were applied to the VPT. Two months postoperatively, visual acuity in the LE improved to 6/10. There was marked regression of the VPT and total resolution of the ERD. In conclusion, we report a favorable visual and clinical outcome in a patient with VPT-associated ERD who responded to a combination of medical therapy and surgical intervention. VPT may lead to different remote complications, so timely diagnosis of these tumors and proper management of their complications is warranted.

摘要

我们报告了一名中年女性的视力和临床结果,该患者患有结节病相关性中间葡萄膜炎,继发于血管增生性肿瘤(VPT)的渗出性视网膜脱离(ERD)。一名先前被诊断为结节病的55岁女性左眼(LE)视力下降。左眼视力为指测。她有活动性葡萄膜炎,颞上周边可见周边视网膜血管肿物。该肿物与累及后极部的渗出性视网膜脱离相关。患者接受全身和玻璃体内类固醇治疗,随后添加环孢素作为类固醇节省剂。由于渗出性视网膜脱离复发,患者接受了玻璃体切除术,并对血管增生性肿瘤进行了冷冻疗法和激光光凝治疗。术后两个月,左眼视力提高到6/10。血管增生性肿瘤明显消退,渗出性视网膜脱离完全消退。总之,我们报告了一名血管增生性肿瘤相关性渗出性视网膜脱离患者,经药物治疗和手术干预联合治疗后,视力和临床结果良好。血管增生性肿瘤可能导致不同的远处并发症,因此对这些肿瘤进行及时诊断并妥善处理其并发症是必要的。

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