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减重手术后的反流、巴雷特食管和食管腺癌

Reflux, Barrett's Esophagus, and Esophageal Adenocarcinoma After Bariatric Surgery.

作者信息

Medina Benjamin, Molena Daniela

机构信息

Memorial Sloan Kettering Cancer Center, New York, NY.

出版信息

Foregut. 2021 Dec;1(4):393-400. doi: 10.1177/26345161211068367. Epub 2022 Jan 7.

Abstract

We present the case of a patient who developed esophageal adenocarcinoma after a previous laparoscopic sleeve gastrectomy. Bariatric surgery has emerged as the most effective treatment option for weight loss and obesity-related diseases; however, sleeve gastrectomy promotes gastroesophageal reflux and leads to Barrett's esophagus in a substantial portion of patients. The natural history of Barrett's esophagus in these patients is unknown, and active surveillance is recommended until the incidence of dysplasia and adenocarcinoma in this population is clarified. Management options for these patients include conversion to Roux-en-Y gastric bypass. Although esophagectomy in patients who have previously undergone sleeve gastrectomy may require an alternative conduit, the remnant stomach can be used in carefully selected patients. Here, we review the different weight loss procedures, their effect on gastroesophageal reflux disease and Barrett's esophagus, and the treatment options for patients with esophageal cancer after sleeve gastrectomy. We report the use of preoperative coil embolization as a means of vascular preconditioning before successful use of a gastric conduit.

摘要

我们报告一例患者,其在先前接受腹腔镜袖状胃切除术后发生了食管腺癌。减重手术已成为治疗体重减轻和肥胖相关疾病最有效的选择;然而,袖状胃切除术会促进胃食管反流,并在相当一部分患者中导致巴雷特食管。这些患者中巴雷特食管的自然病程尚不清楚,在该人群中发育异常和腺癌的发生率明确之前,建议进行积极监测。这些患者的治疗选择包括转为 Roux-en-Y 胃旁路术。虽然先前接受过袖状胃切除术的患者进行食管切除术可能需要替代管道,但在精心挑选的患者中可以使用残余胃。在此,我们回顾不同的减重手术、它们对胃食管反流病和巴雷特食管的影响,以及袖状胃切除术后食管癌患者的治疗选择。我们报告了术前使用线圈栓塞作为成功使用胃管道之前的血管预处理方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7704/11031263/62d587515c5a/nihms-1935188-f0001.jpg

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Treatment of esophageal adenocarcinoma in patients with a history of bariatric surgery.肥胖症手术治疗后食管腺癌的治疗。
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