Macoir Joël, Tremblay Pascale, Beaudoin Stéphanie, Parent Mathias, Hudon Carol
Faculté de Médecine, École des Sciences de la Réadaptation, Université Laval, Québec, QC, Canada.
Centre de Recherche CERVO-Brain Research Centre, Québec, QC, Canada.
Appl Neuropsychol Adult. 2024 Apr 22:1-11. doi: 10.1080/23279095.2024.2344636.
Subjective cognitive decline (SCD) may serve as an early indicator of Alzheimer's disease (AD). However, accurately quantifying cognitive impairment in SCD is challenging, mainly because existing assessment tools lack sensitivity. This study examined how tasks specifically designed to assess knowledge of famous people, could potentially aid in identifying cognitive impairment in SCD. A total of 60 adults with SCD and 60 healthy controls (HCs) aged 50 to 82 years performed a famous people verbal fluency task and a famous people naming task. In the famous people fluency task, the results showed that the individuals with SCD produced significantly fewer famous names in the total time allowed than the HCs, and this difference was also found in the first and the second time interval. In the famous people naming task, the performance of the SCD group was significantly lower than that of the HC group only in the more recent period of fame. Overall, these results suggest that retrieving the names of famous people was more difficult for people with SCD than for people without cognitive complaints. They also suggest that famous people verbal fluency and naming tasks could be useful in detecting cognitive decline at the preclinical stage of AD.
主观认知下降（SCD）可能是阿尔茨海默病（AD）的早期指标。然而，准确量化SCD中的认知障碍具有挑战性，主要是因为现有的评估工具缺乏敏感性。本研究探讨了专门设计用于评估名人知识的任务如何可能有助于识别SCD中的认知障碍。共有60名年龄在50至82岁之间的患有SCD的成年人以及60名健康对照者（HCs）进行了名人言语流畅性任务和名人命名任务。在名人流畅性任务中，结果显示，患有SCD的个体在规定的总时间内说出的名人名字明显少于HCs，并且在第一个和第二个时间间隔中也发现了这种差异。在名人命名任务中，SCD组的表现仅在名人知名度较高的近期显著低于HC组。总体而言，这些结果表明，对于患有SCD的人来说，回忆名人名字比没有认知问题的人更困难。它们还表明，名人言语流畅性和命名任务可能有助于在AD临床前阶段检测认知下降。
