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视觉模式替代疗法与眼动脱敏再处理疗法对比等待列表治疗创伤后应激障碍:一项随机临床试验的结果

Visual Schema Displacement Therapy versus Eye Movement Desensitization and Reprocessing therapy versus waitlist in the treatment of post-traumatic stress disorder: results of a randomized clinical trial.

作者信息

Matthijssen Suzy J M A, Brouwers Thomas C, de Jongh Ad

机构信息

Altrecht Academic Anxiety Centre, Altrecht Geestelijke Gezondheidszorg (GGz), Utrecht, Netherlands.

Psychotrauma (PSYTREC), Bilthoven, Netherlands.

出版信息

Front Psychiatry. 2024 Mar 26;15:1377108. doi: 10.3389/fpsyt.2024.1377108. eCollection 2024.

Abstract

INTRODUCTION

Visual Schema Displacement Therapy (VSDT) is a novel approach showing promise in mitigating distressing memories, akin to Eye Movement Desensitization and Reprocessing (EMDR).

OBJECTIVES

This study aimed to determine the safety, feasibility, and effectiveness of VSDT in individuals with post-traumatic stress disorder (PTSD), comparing it to EMDR therapy and a waitlist control condition (WLCC). It was hypothesized that the application of VSDT would be safe and PTSD symptoms significantly be reduced from both baseline to post-treatment and from baseline to follow-up in the VSDT and EMDR therapy conditions. Furthermore, we expected both treatments to be significantly more effective than the waitlist control. Moreover, we hypothesized that VSDT and EMDR therapy would be associated with significant improvements in symptoms of depression and general psychopathology.

METHOD

Forty-six adults with PTSD were randomly assigned to VSDT, EMDR therapy, or WLCC, receiving six 90-minute sessions. Assessments included the Clinician Administered PTSD Scale for the Diagnostic Statistical Manual (DSM)-5 (CAPS-5), PTSD Checklist for DSM-5 (PCL-5), Beck Depression Inventory-II (BDI-II) and Brief Symptom Inventory (BSI) before, during, and 3 months post-treatment.

RESULTS

Bayesian analysis found no differences between VSDT and EMDR in PTSD symptom reduction but both outperformed WLCC. EMDR was superior to the WLCC in reducing symptoms of depression and general psychopathology. At 3-month follow-up, 58.3% of the participants in the VSDT condition no longer met the PTSD diagnostic criteria (41.2% EMDR therapy and 15.4% WLCC) with no difference between the two therapy conditions. Self-reported PTSD symptom reduction was significant in VSDT (d = 1.38) and EMDR (d = 1.40) but modest in WLCC (d = 0.39). Dropout rate was 19.3%, with no adverse events.

CONCLUSION

This study supports VSDT's efficacy in treating PTSD, offering a valuable therapeutic option comparable to EMDR, with significant reductions in PTSD symptoms and no difference with EMDR or the control condition for depressive symptoms and general psychopathology, and no reported adverse events.

摘要

引言

视觉模式置换疗法(VSDT)是一种新方法,在减轻痛苦记忆方面显示出前景,类似于眼动脱敏再处理疗法(EMDR)。

目的

本研究旨在确定VSDT对创伤后应激障碍(PTSD)患者的安全性、可行性和有效性,并将其与EMDR疗法及等待名单对照条件(WLCC)进行比较。研究假设,VSDT的应用将是安全的,且在VSDT和EMDR疗法条件下,从基线到治疗后以及从基线到随访,PTSD症状会显著减轻。此外,我们预期两种治疗方法都比等待名单对照更有效。而且,我们假设VSDT和EMDR疗法将与抑郁症状和一般精神病理学症状的显著改善相关。

方法

46名患有PTSD的成年人被随机分配到VSDT组、EMDR疗法组或WLCC组,接受六个90分钟的疗程。评估包括在治疗前、治疗期间和治疗后3个月使用针对《精神疾病诊断与统计手册》(DSM)-5的临床医生管理的PTSD量表(CAPS-5)、DSM-5的PTSD检查表(PCL-5)、贝克抑郁量表第二版(BDI-II)和简明症状量表(BSI)。

结果

贝叶斯分析发现,VSDT和EMDR在减轻PTSD症状方面没有差异,但两者都优于WLCC。EMDR在减轻抑郁症状和一般精神病理学症状方面优于WLCC。在3个月的随访中,VSDT组58.3%的参与者不再符合PTSD诊断标准(EMDR疗法组为41.2%,WLCC组为15.4%),两种治疗条件之间没有差异。自我报告的PTSD症状减轻在VSDT组(d = 1.38)和EMDR组(d = 1.40)中显著,但在WLCC组中适度(d = 0.39)。脱落率为19.3%,无不良事件。

结论

本研究支持VSDT治疗PTSD的疗效,提供了一种与EMDR疗法可比的有价值的治疗选择,PTSD症状显著减轻,在抑郁症状和一般精神病理学方面与EMDR或对照条件无差异,且无不良事件报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54e0/11034632/29013ebc01e7/fpsyt-15-1377108-g001.jpg

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