Comprehensive Center for Bronchopulmonary Dysplasia, Nationwide Children's Hospital and Department of Pediatrics, The Ohio State University, Columbus, OH, USA.
The BPD Program at Seattle Children's Hospital and the Department of Pediatrics, University of Washington, Seattle, WA, USA.
J Perinatol. 2024 Jul;44(7):995-1000. doi: 10.1038/s41372-024-01955-x. Epub 2024 Apr 23.
Routine blood gas measurements are common in infants with severe bronchopulmonary dysplasia (sBPD) and are a noxious stimulus. We developed a guideline-driven approach to evaluate the care of infants with sBPD without routine blood gas sampling in the chronic phase of NICU care (after diagnosis at 36 weeks PMA).
We examined blood gas utilization and outcomes in our sBPD inpatient care unit using data collected between 2014 and 2020.
485 sBPD infants met inclusion criteria, and 303 (62%) never had a blood gas obtained after 36 weeks PMA. In infants who had blood gas measurements, the median number of total blood gases per patient was only 4 (IQR 1-10). We did not identify adverse effects on hospital outcomes in patients without routine blood gas measurements.
We found that patients with established BPD could be managed without routine blood gas analyses after 36 weeks PMA.
严重支气管肺发育不良（sBPD）患儿常需进行血气常规检测，但这是一种有害刺激。我们制定了一项指南驱动的方法，以评估在新生儿重症监护病房（NICU）慢性期（36 周校正胎龄后确诊后）护理中无需常规血气采样即可评估 sBPD 患儿的护理情况。
我们使用 2014 年至 2020 年间收集的数据，检查了我们的 sBPD 住院患者护理单元中血气使用情况和结局。
485 名 sBPD 婴儿符合纳入标准，其中 303 名（62%）在 36 周 PMA 后从未进行过血气检测。在进行血气测量的婴儿中，每位患者的总血气测量中位数仅为 4 次（IQR 1-10）。我们未发现无常规血气测量的患者住院结局有不良影响。
我们发现，确诊为 BPD 的患者在 36 周 PMA 后无需常规血气分析即可进行管理。
