R.F.K. Children's Evaluation and Rehabilitation Center, Children's Hospital at Montefiore, The University Hospital for Albert Einstein College of Medicine, Bronx, New York, USA.
J Child Adolesc Psychopharmacol. 2024 Aug;34(6):275-277. doi: 10.1089/cap.2024.0004. Epub 2024 Apr 23.
Despite policy emphasis on early identification, many children with Autism are diagnosed late, with some being diagnosed as late as adolescence. The objective of this study was to examine the demographics and clinical characteristics of school-age children and adolescents initially diagnosed with Autism age 7 and older, in an urban, university-affiliated multidisciplinary center that evaluates/treats youth with developmental disabilities. A chart review of all school-age children and adolescents referred for evaluation to determine if the child has developmental disabilities from January 2019 to May 2023 was performed. Of all children evaluated in that period ( = 825), 164 (19.8%) were diagnosed with Autism, 123 (75%) had a previous diagnosis, and 41 (25%) were newly diagnosed with Autism. Patients newly diagnosed with Autism age ≥7 were more likely to be diagnosed with Language Disorder (100% vs. 82%, = 0.001) and Anxiety Disorder (27% vs. 13%, = 0.04), be prescribed with an antidepressant (10% vs. 1%, = 0.03), and less likely to be diagnosed with Intellectual Disabilities (13% vs. 34%, = 0.001) than those who had a previous diagnosis of Autism, with no other differences in demographics or developmental diagnosis between the groups. Of the 136 patients referred for evaluation with a previous diagnosis of Autism, 13 (9.5%) did not meet the criteria for Autism any longer after multidisciplinary evaluations but continued to present developmental disorders, including Language Disorder (100%), attention-deficit/hyperactivity disorder (46%), and Speech Sound Disorder (38%). Of the 87 families who were concerned about Autism (without a previous diagnosis), 32 (36.8%) confirmed the diagnosis of Autism, 9 (1.5%) patients were newly diagnosed with Autism, and there were no parental concerns. In conclusion, in this ethnically diverse group of school-age children and adolescents with developmental disabilities, 25% received an initial diagnosis of Autism after age 7. Similar to previous reports, children who received a later diagnosis were more likely to present a language impairment, anxiety, and higher cognitive skills. Longitudinal studies, in ethnically diverse populations, are necessary to understand the trajectory and clinical profile of Autism.
尽管政策强调早期识别,但许多自闭症儿童的诊断仍较晚,有些儿童直到青春期才被诊断出来。本研究的目的是检查在一个城市的、多学科的、专门评估/治疗发育障碍青少年的机构中,年龄在 7 岁及以上首次被诊断为自闭症的学龄儿童和青少年的人口统计学和临床特征。对 2019 年 1 月至 2023 年 5 月期间因发育障碍而接受评估的所有学龄儿童和青少年的图表进行了回顾,以确定该儿童是否患有发育障碍。在该期间接受评估的所有儿童中( = 825),164 人(19.8%)被诊断为自闭症,123 人(75%)有先前的诊断,41 人(25%)为新诊断的自闭症。年龄在 7 岁及以上新诊断为自闭症的患者更有可能被诊断为语言障碍(100%比 82%, = 0.001)和焦虑障碍(27%比 13%, = 0.04),接受抗抑郁药治疗(10%比 1%, = 0.03),而不是那些以前被诊断为自闭症的患者,两组在人口统计学或发育诊断方面没有其他差异。在因以前被诊断为自闭症而被转介评估的 136 名患者中,13 名(9.5%)在多学科评估后不再符合自闭症标准,但继续存在发育障碍,包括语言障碍(100%)、注意缺陷多动障碍(46%)和言语语音障碍(38%)。在 87 个对自闭症(无先前诊断)表示担忧的家庭中,32 个(36.8%)确认了自闭症的诊断,9 个(1.5%)患者新诊断为自闭症,且没有父母的担忧。总之,在这个具有发育障碍的、种族多样化的学龄儿童和青少年群体中,有 25%的人在 7 岁后首次被诊断为自闭症。与之前的报告类似,接受较晚诊断的儿童更有可能出现语言障碍、焦虑和更高的认知技能。在种族多样化的人群中进行纵向研究,对于了解自闭症的轨迹和临床特征是必要的。