Røe Anne Berit, Jullumstrø Sidsel, Eig Kristin Brobakken, Lydersen Stian, Nærland Terje, Høyland Anne Lise
Habiliteringstjenesten for barn og unge, St. Olavs hospital.
Habiliteringstjenesten for voksne, St. Olavs hospital.
Tidsskr Nor Laegeforen. 2024 Dec 3;144(15). doi: 10.4045/tidsskr.24.0259. Print 2024 Dec 17.
We have previously reported a significantly higher prevalence of autism spectrum disorders in southern Trøndelag among preschool children with mothers from a different national background than Norway. In this study, we wanted to investigate whether, in the same period and in the same geographic area, there was also an excess prevalence among school-age children. Additionally, we wanted to identify psychiatric and developmental comorbidities.
We carried out a retrospective review of the medical records of children between 10 and 16 years of age who had been diagnosed with autism in the period 2016-19.
Out of a sample of 125 children, 18 had mothers with a different national background. This gave an incidence rate of 0.18 %, against 0.12 % for children with mothers born in Norway (relative risk 1.5; 95 % confidence interval 0.87 to 2.50, p = 0.11). A total of 74 children had been diagnosed with at least one other developmental disorder or psychiatric condition, most commonly ADHD, before they received the autism diagnosis. In four children, the autism spectrum disorder was accompanied by an intellectual disability.
Maternal national background appears to be a less significant factor among school-age children than among preschool children who receive an autism spectrum diagnosis, and age at the time of diagnosis should be specified in studies on autism in children and adolescents. Psychiatric comorbidity and other accompanying developmental disorders may suggest shared aetiological factors or increased vulnerability in cases of undiagnosed autism in children.
我们之前曾报道,在南特伦德拉格郡,母亲具有非挪威国籍背景的学龄前儿童患自闭症谱系障碍的患病率显著更高。在本研究中,我们想调查在同一时期、同一地理区域,学龄儿童中是否也存在过高的患病率。此外,我们想确定精神疾病和发育方面的共病情况。
我们对2016年至2019年期间被诊断为自闭症的10至16岁儿童的病历进行了回顾性研究。
在125名儿童样本中,18名儿童的母亲具有不同国籍背景。这得出的发病率为0.18%,而母亲出生在挪威的儿童发病率为0.12%(相对风险1.5;95%置信区间0.87至2.50,p = 0.11)。共有74名儿童在被诊断为自闭症之前被诊断出至少患有一种其他发育障碍或精神疾病,最常见的是注意力缺陷多动障碍(ADHD)。在4名儿童中,自闭症谱系障碍伴有智力残疾。
在学龄儿童中,母亲的国籍背景似乎不如在接受自闭症谱系诊断的学龄前儿童中那样是一个重要因素,并且在儿童和青少年自闭症研究中应明确诊断时的年龄。精神疾病共病和其他伴随的发育障碍可能表明在未确诊的儿童自闭症病例中存在共同的病因因素或更高的易感性。