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基于晶格结构和 ZIRCONIA/CaSiO 组合的 3D 打印超短牙科植入物。

A 3D printed ultra-short dental implant based on lattice structures and ZIRCONIA/CaSiO combination.

机构信息

School of Mechanical Engineering, University of Birmingham, Birmingham, UK; Lecturer, Dental Biomaterials, Restorative and Prosthodontic Dental Sciences Department, School of Dentistry, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs Riyadh, P.O. Box 24264, Riyadh, 11486, Kingdom of Saudi Arabia.

School of Mechanical Engineering, University of Birmingham, Birmingham, UK.

出版信息

J Mech Behav Biomed Mater. 2024 Jul;155:106559. doi: 10.1016/j.jmbbm.2024.106559. Epub 2024 Apr 21.

DOI:10.1016/j.jmbbm.2024.106559
PMID:38657285
Abstract

Additive Manufacturing (AM) enables the generation of complex geometries and controlled internal cavities that are so interesting for the biomedical industry due to the benefits they provide in terms of osseointegration and bone growth. These technologies enable the manufacturing of the so-called lattice structures that are cells with different geometries and internal pores joint together for the formation of scaffold-type structures. In this context, the present paper analyses the feasibility of using diamond-type lattice structures and topology optimisation for the re-design of a dental implant. Concretely, a new ultra-short implant design is proposed in this work. For the manufacturing of the implant, digital light processing additive manufacturing technique technology is considered. The implant was made out of Nano-zirconia and Nano-Calcium Silicate as an alternative material to the more common Ti6Al4V. This material combination was selected due to the properties of the calcium-silicate that enhance bone ingrowth. The influence of different material combination ratios and lattice pore sizes were analysed by means of FEM simulation. For those simulations, a bio-material bone-nanozirconia model was considered that represents the final status after the bone is integrated in the implant. Results shows that the mechanical properties of the biocompatible composite employed were suitable for dental implant applications in dentistry. Based on the obtained results it was seen that those designs with 400 μm and 500 μm pore sizes showed best performance and led to the required factor of safety.

摘要

增材制造(AM)能够生成复杂的几何形状和受控的内部空腔,这对于生物医学行业非常有趣,因为它们在骨整合和骨生长方面提供了益处。这些技术能够制造出所谓的晶格结构,这些结构是由不同几何形状和内部孔的细胞连接在一起形成支架型结构。在这种情况下,本文分析了使用钻石型晶格结构和拓扑优化来重新设计牙科植入物的可行性。具体来说,这项工作提出了一种新的超短植入物设计。为了制造植入物,考虑使用数字光处理增材制造技术。植入物由纳米氧化锆和纳米硅酸钙制成,作为比更常见的 Ti6Al4V 更常见的替代材料。选择这种材料组合是因为硅酸钙的特性可以增强骨向内生长。通过有限元模拟分析了不同材料组合比和晶格孔尺寸的影响。对于这些模拟,考虑了代表植入物中骨骼整合后的最终状态的生物材料骨-纳米氧化锆模型。结果表明,所使用的生物相容性复合材料的机械性能适用于牙科植入物在牙科中的应用。根据获得的结果可以看出,那些具有 400μm 和 500μm 孔径的设计表现最好,达到了所需的安全系数。

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