Thrombosis and Healthy Aging Research Center, Medical Technology School, Department of Clinical Biochemistry and Immunohematology, Faculty of Health Sciences, Universidad de Talca, Talca 3480094, Chile.
REGICOR Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain; CIBERESP de investigación en Epidemiología y Salud Pública, Madrid, Spain; CIBERCV de investigación en Enfermedades Cardiovasculares, Madrid, Spain.
Geriatr Nurs. 2024 May-Jun;57:154-162. doi: 10.1016/j.gerinurse.2024.04.011. Epub 2024 Apr 24.
The study of frailty and its effect on the risk of mortality in older people is of utmost importance, but understanding the critical factors is still limited. Our main objective was to analyze the association of frailty with all-cause mortality in a prospective community cohort of older people.
A five-year longitudinal follow-up study was conducted with 1,174 community-dwelling older adults (men and women≥65 years old) from different Family Health Centers and community groups from Chile. We evaluated the functional risk, socioeconomic status, and anthropometric variables. The frailty status was evaluated by modified Fried criteria.
The diagnosis of frailty was reached in 290 older adult participants, who had significantly increased 5-year all-cause mortality independently of age, sex, cognitive impairment, and socioeconomic status (adjusted HR 1.51, 1.06-2.15).
Frailty is a predictor of increased mortality independently of age, sex, socio-economic and cognitive factors.
研究衰弱及其对老年人死亡率风险的影响至关重要，但对关键因素的理解仍有限。我们的主要目的是分析衰弱与前瞻性社区老年人群全因死亡率的相关性。
对来自智利不同家庭健康中心和社区团体的 1174 名社区居住的老年人（男女≥65 岁）进行了为期 5 年的纵向随访研究。我们评估了功能风险、社会经济状况和人体测量变量。采用改良 Fried 标准评估衰弱状况。
290 名老年参与者被诊断为衰弱，他们的 5 年全因死亡率显著增加，独立于年龄、性别、认知障碍和社会经济状况（调整后的 HR 为 1.51，1.06-2.15）。
衰弱是独立于年龄、性别、社会经济和认知因素的死亡率增加的预测因子。
