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COVID-19 感染患者发生致命性全身毛细血管渗漏综合征。

Fatal Systemic Capillary Leak Syndrome in a Patient with a COVID-19 Infection.

机构信息

Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.

Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.

出版信息

Intern Med. 2024 Jul 1;63(13):1893-1897. doi: 10.2169/internalmedicine.3637-24. Epub 2024 Apr 23.

Abstract

A 29-year-old Japanese woman was admitted to our hospital with a fever, cardiogenic shock, and cardiac arrest. Laboratory data indicated multiple organ failure in addition to hemoconcentration, hypoalbuminemia, and myocardial damage. The coronary angiography findings were normal, and fulminant myocarditis was suspected. Venoarterial peripheral extracorporeal membrane oxygenation and an Impella CP left ventricular assist device were initiated, along with the administration of positive inotropic agents. However, hypovolemic shock and hypoalbuminemia progressed along with severe anemia, and the patient died 18 hours after admission. The patient was diagnosed with systemic capillary leak syndrome associated with coronavirus disease 2019.

摘要

一位 29 岁的日本女性因发热、心源性休克和心脏骤停而被收入我院。实验室数据除了提示血液浓缩、低白蛋白血症和心肌损伤外,还表明存在多器官衰竭。冠状动脉造影结果正常,疑似暴发性心肌炎。我们开始使用静脉动脉外周体外膜肺氧合和 Impella CP 左心室辅助设备,并给予正性肌力药物。然而,低血容量性休克和低白蛋白血症随着严重贫血而进展,患者在入院后 18 小时死亡。该患者被诊断为与 2019 年冠状病毒病相关的全身性毛细血管渗漏综合征。

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