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COVID-19 感染患者发生致命性全身毛细血管渗漏综合征。

Fatal Systemic Capillary Leak Syndrome in a Patient with a COVID-19 Infection.

机构信息

Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.

Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.

出版信息

Intern Med. 2024 Jul 1;63(13):1893-1897. doi: 10.2169/internalmedicine.3637-24. Epub 2024 Apr 23.

DOI:10.2169/internalmedicine.3637-24
PMID:38658337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11272515/
Abstract

A 29-year-old Japanese woman was admitted to our hospital with a fever, cardiogenic shock, and cardiac arrest. Laboratory data indicated multiple organ failure in addition to hemoconcentration, hypoalbuminemia, and myocardial damage. The coronary angiography findings were normal, and fulminant myocarditis was suspected. Venoarterial peripheral extracorporeal membrane oxygenation and an Impella CP left ventricular assist device were initiated, along with the administration of positive inotropic agents. However, hypovolemic shock and hypoalbuminemia progressed along with severe anemia, and the patient died 18 hours after admission. The patient was diagnosed with systemic capillary leak syndrome associated with coronavirus disease 2019.

摘要

一位 29 岁的日本女性因发热、心源性休克和心脏骤停而被收入我院。实验室数据除了提示血液浓缩、低白蛋白血症和心肌损伤外,还表明存在多器官衰竭。冠状动脉造影结果正常,疑似暴发性心肌炎。我们开始使用静脉动脉外周体外膜肺氧合和 Impella CP 左心室辅助设备,并给予正性肌力药物。然而,低血容量性休克和低白蛋白血症随着严重贫血而进展,患者在入院后 18 小时死亡。该患者被诊断为与 2019 年冠状病毒病相关的全身性毛细血管渗漏综合征。

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本文引用的文献

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Two cases of systemic capillary leak syndrome associated with COVID-19 in Japan.日本两例与新冠病毒病相关的系统性毛细血管渗漏综合征病例。
J Infect Chemother. 2024 Mar;30(3):250-254. doi: 10.1016/j.jiac.2023.10.005. Epub 2023 Oct 14.
2
Systemic Capillary Leak Syndrome as a Rare, Potentially Fatal Complication of COVID-19: A Case Report and Literature Review.系统性毛细血管渗漏综合征作为新型冠状病毒肺炎一种罕见的、潜在致命的并发症:一例病例报告及文献综述
Cureus. 2023 Aug 2;15(8):e42837. doi: 10.7759/cureus.42837. eCollection 2023 Aug.
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COVID-19 Complicated With Severe Systemic Capillary Leak Syndrome in an Infant.
Systemic capillary leak syndrome.
全身性毛细血管渗漏综合征。
Nat Rev Dis Primers. 2024 Nov 14;10(1):86. doi: 10.1038/s41572-024-00571-5.
一名婴儿新冠病毒肺炎合并严重全身性毛细血管渗漏综合征
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Rapid Progression of COVID-19-Associated Fatal Capillary Leak Syndrome.新型冠状病毒肺炎相关致死性毛细血管渗漏综合征的快速进展
Infect Dis Rep. 2022 Nov 17;14(6):884-888. doi: 10.3390/idr14060088.
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A case of chronic systemic capillary leak syndrome (SCLS) exacerbated during SARS-CoV2 infection.一例慢性全身毛细血管渗漏综合征(SCLS)在 SARS-CoV2 感染期间加重。
Eur Rev Med Pharmacol Sci. 2021 Oct;25(19):5922-5927. doi: 10.26355/eurrev_202110_26868.
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New-Onset Systemic Capillary Leak Syndrome in an Adult Patient with COVID-19.一名新冠肺炎成年患者出现新发系统性毛细血管渗漏综合征
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7
Fatal Exacerbations of Systemic Capillary Leak Syndrome Complicating Coronavirus Disease.冠状病毒病并发全身性毛细血管渗漏综合征的致死性加重。
Emerg Infect Dis. 2021 Oct;27(10):2529-2534. doi: 10.3201/eid2710.211155. Epub 2021 Jul 27.
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