带非球面小透镜的眼镜片对近视儿童脉络膜厚度的影响：一项3年随访研究

Effect of spectacle lenses with aspherical lenslets on choroidal thickness in myopic children: a 3-year follow-up study.

作者信息

Huang Yingying, Li Xue, Zhuo Zuopao, Zhang Jiali, Que Tianxing, Yang Adeline, Drobe Björn, Chen Hao, Bao Jinhua

机构信息

National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang, 325027, China.

Wenzhou Medical University - Essilor International Research Center (WEIRC), Wenzhou Medical University, Wenzhou, Zhejiang, China.

出版信息

Eye Vis (Lond). 2024 Apr 25;11(1):16. doi: 10.1186/s40662-024-00383-4.

DOI:10.1186/s40662-024-00383-4

PMID:38659078

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11044302/

Abstract

BACKGROUND

To investigate the impact of wearing spectacle lenses with highly aspherical lenslets (HAL) for 3 years and the impact of switching from single-vision lenses (SVL) to HAL on choroidal thickness (ChT).

METHODS

Fifty-one participants who had already worn HAL for 2 years continued wearing them for an additional year (HAL group). Further, 50 and 41 participants who had worn spectacle lenses with slightly aspherical lenslets (SAL) and SVL for 2 years, respectively, switched to wearing HAL for another year (SAL-HAL and SVL-HAL groups). Additionally, 48 new participants aged 10-15 years were enrolled to wear SVL at the third year (new-SVL group). ChT was measured every 6 months throughout the study.

RESULTS

Significant differences were observed in the changes in ChT among the four groups at the third year (all P < 0.05 except for the outer nasal region: P = 0.09), with the new-SVL group showing larger reductions compared with the other three groups. However, none of the three HAL-wearing groups showed significant changes in ChT at the third year (all P > 0.05). When comparing the changes in ChT for 3 years among the HAL, SAL-HAL, and SVL-HAL groups, significant differences were found before switching to HAL, but these differences were abolished after all participants switched to HAL.

CONCLUSIONS

Compared to those in the SVL group, choroid thinning was significantly inhibited in all the HAL groups. Wearing HAL for 3 years no longer had a choroidal thickening effect but could still inhibit choroidal thinning compared to wearing SVL.

TRIAL REGISTRATION

The study was registered at the Chinese Clinical Trial Registry (ChiCTR1800017683), http://www.chictr.org.cn/showproj.aspx?proj=29789 .

摘要

背景

研究佩戴具有高非球面微透镜（HAL）的眼镜片3年的影响以及从单焦点镜片（SVL）转换为HAL对脉络膜厚度（ChT）的影响。

方法

51名已佩戴HAL两年的参与者继续佩戴一年（HAL组）。此外，分别佩戴具有轻度非球面微透镜（SAL）和SVL的眼镜片两年的50名和41名参与者转换为佩戴HAL再持续一年（SAL-HAL组和SVL-HAL组）。另外，招募了48名年龄在10 - 15岁的新参与者在第三年佩戴SVL（新-SVL组）。在整个研究过程中每6个月测量一次ChT。

结果

在第三年时，四组之间ChT的变化存在显著差异（除鼻外侧区域外，所有P < 0.05：P = 0.09），新-SVL组与其他三组相比ChT降低幅度更大。然而，三个佩戴HAL的组在第三年时ChT均未显示出显著变化（所有P > 0.05）。当比较HAL组、SAL-HAL组和SVL-HAL组3年的ChT变化时，在转换为HAL之前发现了显著差异，但在所有参与者都转换为HAL后这些差异消失了。