Nagylaki T
Proc Natl Acad Sci U S A. 1985 Dec;82(24):8611-3. doi: 10.1073/pnas.82.24.8611.
The amount and pattern of genetic variability in a geographically structured population at equilibrium under the joint action of migration, mutation, and random genetic drift is studied. The monoecious, diploid population is subdivided into panmictic colonies that exchange migrants. Self-fertilization does not occur; generations are discrete and nonoverlapping; the analysis is restricted to a single locus in the absence of selection; every allele mutates to new alleles at the same rate. It is shown that if the number of demes is finite and migration does not alter the deme sizes, then population subdivision produces interdeme differentiation and the mean homozygosity and the effective number of alleles exceed their panmictic values. A simple relation between the mean probability of identity and the mean homozygosity is established. The results apply to a dioecious population if the migration pattern and mutation rate are sex independent.
研究了在迁移、突变和随机遗传漂变的共同作用下，处于平衡状态的地理结构种群中的遗传变异性数量和模式。该雌雄同株的二倍体种群被细分为进行移民交换的随机交配群体。不存在自体受精；世代是离散且不重叠的；分析限于无选择情况下的单个基因座；每个等位基因以相同速率突变为新等位基因。结果表明，如果群体数量有限且迁移不改变群体大小，那么种群细分会产生群体间分化，平均纯合度和等位基因有效数量超过其随机交配时的值。建立了平均同一概率与平均纯合度之间的简单关系。如果迁移模式和突变率与性别无关，这些结果适用于雌雄异株种群。
