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肠道脱硫弧菌对宿主健康的影响及其潜在的调控策略:综述。

Effects of intestinal Desulfovibrio bacteria on host health and its potential regulatory strategies: A review.

机构信息

College of Food Science, Southwest University, Chongqing 400715, China.

National Key Laboratory of Market Supervision (Condiment Supervision Technology), Chongqing Institute for Food and Drug Control, Chongqing 401121, China.

出版信息

Microbiol Res. 2024 Jul;284:127725. doi: 10.1016/j.micres.2024.127725. Epub 2024 Apr 12.

Abstract

Increasing studies have focused on the relationship between Desulfovibrio bacteria (DSV) and host health in recent years. However, little is known about the mechanisms by which DSV affects host health and the strategies to accurately regulate DSV numbers. This review mainly presents the relationship between DSV and host health, potential modulatory strategies, and the potential mechanisms affecting host health. Evidence suggests that DSV can both promote host health and induce the occurrence and development of disease, and these effects are closely related to its metabolites (e.g., HS and short-chain fatty acids) and biofilm. DSV abundance in the intestine is influenced by probiotics, prebiotics, diet, lifestyle, and drugs.

摘要

近年来,越来越多的研究关注脱硫弧菌(Desulfovibrio bacteria,DSV)与宿主健康之间的关系。然而,人们对 DSV 影响宿主健康的机制以及准确调控 DSV 数量的策略知之甚少。本综述主要介绍了 DSV 与宿主健康的关系、潜在的调控策略以及影响宿主健康的潜在机制。有证据表明,DSV 既能促进宿主健康,又能诱发疾病的发生和发展,这些影响与其代谢物(如 HS 和短链脂肪酸)和生物膜密切相关。肠道中 DSV 的丰度受益生菌、益生元、饮食、生活方式和药物的影响。

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