National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University, Wuhan 430070, PR China.
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Curr Opin Plant Biol. 2024 Jun;79:102541. doi: 10.1016/j.pbi.2024.102541. Epub 2024 Apr 25.
Messenger RNAs (mRNAs) are the templates for protein translation but can also act as non-cell-autonomous signaling molecules. Plants input endogenous and exogenous cues to mobile mRNAs and output them to local or systemic target cells and organs to support specific plant responses. Mobile mRNAs form ribonucleoprotein (RNP) complexes with proteins during transport. Components of these RNP complexes could interact with plasmodesmata (PDs), a major mediator of mRNA transport, to ensure mRNA mobility and transport selectivity. Based on advances in the last two to three years, this review summarizes mRNA transport mechanisms in local and systemic signaling from the perspective of RNP complex formation and PD transport. We also discuss the physiological roles of endogenous mRNA transport and the recently revealed roles of non-cell-autonomous mRNAs in inter-organism communication.
信使 RNA（mRNA）是蛋白质翻译的模板，但也可以作为非细胞自主的信号分子发挥作用。植物将内源性和外源性信号输入到可移动的 mRNA 中，并将其输出到局部或系统靶细胞和器官，以支持特定的植物反应。在运输过程中，可移动的 mRNA 与蛋白质形成核糖核蛋白（RNP）复合物。这些 RNP 复合物的组成部分可以与胞间连丝（PD）相互作用，胞间连丝是 mRNA 运输的主要介导物，以确保 mRNA 的流动性和运输的选择性。基于过去两到三年的进展，本综述从 RNP 复合物形成和 PD 运输的角度总结了局部和系统信号中 mRNA 运输的机制。我们还讨论了内源性 mRNA 运输的生理作用以及最近发现的非细胞自主 mRNA 在生物间通讯中的作用。
