Federal University of Rio Grande Do Norte, Natal, Rio Grande Do Norte, Brazil.
Language and Hearing Sciences, Federal University of Rio Grande Do Norte, Natal, Rio Grande Do Norte, Brazil.
Clin Oral Investig. 2024 Apr 26;28(5):274. doi: 10.1007/s00784-024-05642-1.
This study aims to determine the association between severe mental disorders and oral health among individuals over 18 years of age.
An electronic search was conducted in six electronic databases and gray literature. Qualitative and quantitative analyses were performed on studies that met the inclusion criteria. The methodology of the included studies was assessed using the Joanna Briggs Institute Critical Appraisal tool. A meta-analysis of proportions with a random effect was carried out. The certainty of evidence was evaluated using the GRADE tool.
After searching the databases, 5,734 references were retrieved, and twenty articles were selected for synthesis. Considering the DMFT index between the groups with mental disorders and the control group, the values of the DMFT index were higher among individuals with schizophrenia [MD = 5.27; 95% CI = 4.13 - 6.42; I = 35%] and bipolar disorder [MD = 1.90; 95% CI = 0.87 - 2.93]. Values were lower among individuals with obsessive-compulsive disorder [MD = -0.85; 95% CI = -1.46-0.24]. The risk of bias was considered low for 16 studies, and four were classified with a moderate risk of bias. The certainty of evidence was very low.
Patients with schizophrenia and bipolar disorder exhibit increased frequency in the number of decayed, missing, or filled teeth. There was no effect in relation to periodontal probing depth, plaque index, and TMD, but the evidence is still uncertain for this outcome.
These findings underscore the need for a comprehensive health approach.
本研究旨在确定 18 岁以上个体严重精神障碍与口腔健康之间的关联。
在六个电子数据库和灰色文献中进行电子检索。对符合纳入标准的研究进行定性和定量分析。使用 Joanna Briggs 研究所的批判性评估工具评估纳入研究的方法学。采用随机效应的比例进行荟萃分析。使用 GRADE 工具评估证据的确定性。
在数据库搜索后,共检索到 5734 篇参考文献,并选择了 20 篇文章进行综合分析。考虑到精神障碍组和对照组之间的 DMFT 指数,精神分裂症患者的 DMFT 指数值更高[MD=5.27;95%置信区间(CI)=4.13-6.42;I=35%],双相情感障碍患者的 DMFT 指数值更高[MD=1.90;95%CI=0.87-2.93]。强迫症患者的 DMFT 指数值较低[MD=-0.85;95%CI=-1.46-0.24]。16 项研究的偏倚风险被认为较低,4 项研究的偏倚风险被归类为中度。证据的确定性非常低。
精神分裂症和双相情感障碍患者的龋齿、失牙或补牙数量增加。牙周探诊深度、菌斑指数和 TMD 无影响,但该结果的证据仍不确定。
这些发现强调了需要采取综合健康方法。