Miles P A, Herrera G A, Mena H, Trujillo I
Acta Cytol. 1985 Nov-Dec;29(6):1003-8.
The cytologic findings in a primary malignant carcinoid tumor of the cervix are presented. In addition to the presence in the smears of cells suggestive of squamous carcinoma and adenocarcinoma, which led to an initial diagnosis of adenosquamous carcinoma, there were multinucleated giant cells with prominent, reddish nucleoli, finely granular chromatin and grayish-blue to eosinophilic cytoplasm, as well as smaller pleomorphic cells, against a tumor-diathesis type of background. Immunocytochemistry performed on the cervical smears showed the presence of serotonin, and ultrastructural analysis revealed abundant intracytoplasmic, membrane-bound granules in malignant cells, thus confirming the diagnosis of a carcinoid tumor.
本文报告了一例宫颈原发性恶性类癌肿瘤的细胞学检查结果。涂片中有提示鳞状细胞癌和腺癌的细胞，最初诊断为腺鳞癌，此外还有多核巨细胞，其核仁突出、呈红色，染色质细颗粒状，胞质呈灰蓝色至嗜酸性，以及较小的多形性细胞，背景为肿瘤素质类型。对宫颈涂片进行的免疫细胞化学检查显示存在血清素，超微结构分析显示恶性细胞内有丰富的胞质内、膜结合颗粒，从而确诊为类癌肿瘤。
