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[西伯利亚旅鼠和中田鼠对波摩那群钩端螺旋体的易感性与敏感性]

[Susceptibility and sensitivity of the Siberian lemming and Middendorff's vole to leptospirae of the grippotyphosa serogroup].

作者信息

Litvin V Iu, Alekseeva I P

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1979 Aug(8):90-4.

PMID:386660
Abstract

Siberian lemmings and Middendorf's voles were found to be susceptible to infection caused by Leptospira of the Grippotyphosa serogroup after the intraperitoneal injection of Leptospira culture, the application of the culture or infected urine to the skin, as well as after Leptospira-carrying animals were placed together with the animals to be infected. The infectious sensitivity of these animals to Leptospira was not high: leptospiruria was observed for 1-3 weeks; in some of the voles leptospiruria was slightly pronounced, whereas other voles had a great number of Leptospira in urine. Antibodies appeared in the blood on day 5 after infection, and their titers increased till days 61-63. In no case could Leptospira be isolated from the kidneys of the animals killed on days 61-83 of the experiment.

摘要

在腹腔注射钩端螺旋体培养物、将培养物或感染尿液涂抹于皮肤以及将携带钩端螺旋体的动物与待感染动物放在一起之后,发现西伯利亚旅鼠和中田鼠对波摩那群钩端螺旋体引起的感染易感。这些动物对钩端螺旋体的感染敏感性不高:钩端螺旋体尿持续1至3周;在一些田鼠中,钩端螺旋体尿表现轻微,而在其他田鼠的尿液中有大量钩端螺旋体。感染后第5天血液中出现抗体,其滴度在第61至63天之前不断升高。在实验第61至83天处死的动物肾脏中,均未分离出钩端螺旋体。

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