用于检测铜（II）离子的高选择性和高灵敏度荧光探针及其在体外和体内的生物成像。
The highly selective and sensitive fluorescence probe for detection of copper (II) ions and its bioimaging in vitro and vivo.
机构信息
College of Laboratory Medicine, Zhang Jiakou Key Laboratory of Organic Light Functional Materials, Hebei Key Laboratory of Neuropharmacology and Hebei Key Laboratory of Quality & Safety Analysis-Testing for Agro-Products and Food, Hebei North University, Zhangjiakou, 075000, Hebei Province, People's Republic of China.
Zhangjiakou No. 1 Middle School, Zhangjiakou, 075000, Hebei Province, People's Republic of China.
出版信息
Spectrochim Acta A Mol Biomol Spectrosc. 2024 Aug 5;316:124328. doi: 10.1016/j.saa.2024.124328. Epub 2024 Apr 23.
We designed and developed the probe W-3 for detection of Cu. The results showed probe can selectively detect Cu, accompanied by noticeable color change. The probe can detect the Cu in water samples and drinks based on absorption detection. In addition, the combination of portable test paper and the smartphone platform obtained great convenience for on-site and visual detection of Cu, with satisfactory sensitivity and reliability. More importantly, the fluorescence probe W-3 can be used for the detection of Cu in cells and mice. Therefore, the W-3 provided potential chemical tools for detecting Cu in vitro and vivo.
我们设计并开发了用于检测 Cu 的探针 W-3。结果表明，该探针可以选择性地检测 Cu，同时伴随着明显的颜色变化。该探针可以通过吸收检测来检测水样和饮料中的 Cu。此外，便携式试纸与智能手机平台的结合为 Cu 的现场和可视化检测提供了极大的便利，具有令人满意的灵敏度和可靠性。更重要的是，荧光探针 W-3 可用于检测细胞和小鼠中的 Cu。因此，W-3 为体外和体内检测 Cu 提供了潜在的化学工具。
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