Badurski J
Acta Med Acad Sci Hung. 1978;35(3-4):269-75.
In order to answer the question whether acid alpha 1-glycoprotein (AGP) is produced by the healthy human gastric mucosa, column chromatography of neutralized, pooled, and papain digested normal human gastric juice was performed on DEAE-cellulose using Varigrad NaCl elution gradients. Four glycoprotein fractions were obtained, one of which (fraction III) contained AGP. Its antibody raised in rabbits did not give immunofluorescence with any of the cells of the human gastric mucosa, only a reaction with AGP located in the intercellular spaces of gastric glands. These results indicate the extragastric origin of AGP, probably from serum.
为了回答健康人胃黏膜是否产生酸性α1-糖蛋白（AGP）这一问题，对中和、汇集并用木瓜蛋白酶消化的正常人胃液进行柱色谱分析，采用Varigrad NaCl洗脱梯度在DEAE-纤维素上进行。获得了四个糖蛋白组分，其中一个组分（组分III）含有AGP。在兔体内产生的其抗体与人胃黏膜的任何细胞均未产生免疫荧光，仅与位于胃腺细胞间隙中的AGP发生反应。这些结果表明AGP的胃外来源，可能来自血清。
