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BMC Musculoskelet Disord. 2022 Jul 8;23(1):652. doi: 10.1186/s12891-022-05591-4.
2
Marijuana Use and the Risk of Early Ischemic Stroke: The Stroke Prevention in Young Adults Study.大麻使用与早期缺血性中风的风险:年轻人中风预防研究。
Stroke. 2021 Oct;52(10):3184-3190. doi: 10.1161/STROKEAHA.120.032811. Epub 2021 Jul 16.
3
Hand-arm vibration syndrome: A rarely seen diagnosis.手臂振动综合征:一种罕见的诊断。
J Vasc Surg Cases Innov Tech. 2017 Apr 25;3(2):60-62. doi: 10.1016/j.jvscit.2017.01.002. eCollection 2017 Jun.
4
Vertebral artery dissection following a posterior cervical foraminotomy.后路颈椎椎间孔切开术后椎动脉夹层形成
J Surg Case Rep. 2017 Feb 8;2017(2):rjx014. doi: 10.1093/jscr/rjx014. eCollection 2017 Feb.
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Radiation-induced carotid artery stenosis: a comprehensive review of the literature.放射性颈动脉狭窄:文献综述
Interv Neurol. 2014 Aug;2(4):183-92. doi: 10.1159/000363068.
6
Complications, outcomes, and need for fusion after minimally invasive posterior cervical foraminotomy and microdiscectomy.微创后路颈椎椎间孔切开术和显微椎间盘切除术术后的并发症、结局及融合需求
Spine J. 2014 Oct 1;14(10):2405-11. doi: 10.1016/j.spinee.2014.01.048. Epub 2014 Jan 30.
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Radiation-induced carotid artery atherosclerosis.辐射诱导的颈动脉粥样硬化。
Radiother Oncol. 2014 Jan;110(1):31-8. doi: 10.1016/j.radonc.2013.08.009. Epub 2013 Sep 14.
8
Metastatic squamous cell carcinoma to the brain: an unrecognized pattern of distant spread in patients with HPV-related head and neck cancer.脑转移鳞状细胞癌:HPV 相关头颈部癌症患者远处转移的一种未被认识到的模式。
J Neurooncol. 2013 May;112(3):449-54. doi: 10.1007/s11060-013-1075-9. Epub 2013 Feb 14.
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Three-month and long-term outcomes and their predictors in acute basilar artery occlusion treated with intra-arterial thrombolysis.急性基底动脉闭塞患者接受动脉内溶栓治疗的三个月及长期预后及其预测因素。
Stroke. 2011 Jul;42(7):1946-51. doi: 10.1161/STROKEAHA.110.606038. Epub 2011 May 5.
10
Cervical artery dissection: emerging risk factors.颈动脉瘤夹层:新出现的危险因素。
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选择性颈椎椎间孔切开术后的闭锁综合征:病例报告。

Locked-in syndrome following elective cervical foraminotomy: a case report.

机构信息

Boston University Medical Center, Boston, MA, USA.

Mount Sinai Hospital, New York, NY, USA.

出版信息

Spinal Cord Ser Cases. 2024 Apr 26;10(1):32. doi: 10.1038/s41394-024-00643-4.

DOI:10.1038/s41394-024-00643-4
PMID:38670974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11053117/
Abstract

INTRODUCTION

There are no previously reported cases of locked-in syndrome occurring following cervical spinal surgery. We describe a case of locked-in syndrome following an elective cervical foraminotomy and discuss potential etiologies and contributing factors to our patient's presentation.

CASE PRESENTATION

A 54-year-old male with a history of head and neck cancer and prior anterior cervical discectomy and fusion presented with neck pain following a motor vehicle accident. The patient underwent C4-C7 left-sided cervical posterior foraminotomy with no intraoperative complications. On postoperative day 1, the patient suddenly developed rapidly progressing weakness of the extremities and soon became non-verbal. CT angiography and near-infrared spectroscopy confirmed a basilar artery occlusion and left vertebral artery dissection. On MRI, infarcts involving the bilateral pons, left cerebral hemisphere, and left cerebellar infarct were identified.

CONCLUSION

The etiology of locked-in syndrome in our patient remains unclear, but it is likely multifactorial. It is possible that the patient was predisposed to vascular injury from prior radiation therapy to the head and neck. In addition, intraoperative vascular insult may have occurred from vibrational shear stress, in turn leading to a vertebral artery dissection, basilar artery occlusion, and pontine infarct, ultimately resulting in our patient's locked-in state.

摘要

简介

颈椎手术后出现闭锁综合征尚无既往报道。我们描述了一例选择性颈椎椎间孔切开术后发生闭锁综合征的病例,并讨论了导致患者出现这种情况的潜在病因和促成因素。

病例介绍

一名 54 岁男性,有头颈部癌症病史,既往行前路颈椎间盘切除术和融合术,因车祸后出现颈部疼痛。患者行 C4-C7 左侧颈椎后路椎间孔切开术,术中无并发症。术后第 1 天,患者突然出现四肢进行性无力,并很快无法言语。CT 血管造影和近红外光谱证实基底动脉闭塞和左侧椎动脉夹层。MRI 显示双侧脑桥、左侧大脑半球和左侧小脑梗死。

结论

我们患者的闭锁综合征的病因仍不清楚,但可能是多因素的。患者可能因头颈部先前接受过放射治疗而容易发生血管损伤。此外,术中血管损伤可能是由于振动剪切力引起的,进而导致椎动脉夹层、基底动脉闭塞和脑桥梗死,最终导致患者出现闭锁状态。