四川汉族人群中的人类白细胞抗原多态性

HLA polymorphisms in a Han Chinese population of Sichuan.

作者信息

Pei J, Tokunaga K, Araki C, Yang C L, Sun S X, Mi X Y, Saji H, Xiao X F, Liang W X, Tokunaga E

出版信息

Tissue Antigens. 1985 Nov;26(5):323-31. doi: 10.1111/j.1399-0039.1985.tb02231.x.

DOI:10.1111/j.1399-0039.1985.tb02231.x

Abstract

This study reports the phenotype frequencies (PF) and gene frequencies (GF) of a homogeneous Sichuan Han Chinese population by typing of unrelated 229 individuals and 16 families for HLA-A, B, C, DR and DQ antigens. The frequencies of Bw67, Bw71, DRw12, DRw13 and DRw14 are the first to be reported in Chinese. Two two-locus haplotypes with significant linkage disequilibrium among the Sichuan have also been listed.

摘要

本研究通过对229名无亲缘关系的个体和16个家庭进行HLA - A、B、C、DR和DQ抗原分型，报告了同质四川汉族人群的表型频率（PF）和基因频率（GF）。Bw67、Bw71、DRw12、DRw13和DRw14的频率在中国尚属首次报道。还列出了四川人群中两个具有显著连锁不平衡的两位点单倍型。