Bissolotti Luciano, Artiles-Sánchez Justo, Alonso-Pérez José Luís, Fernández-Carnero Josué, Abuín-Porras Vanesa, Sinatti Pierluigi, Villafañe Jorge Hugo
Fondazione Teresa Camplani Casa di Cura Domus Salutis, 25123 Brescia, Italy.
Musculoskeletal Pain and Motor Control Research Group, Faculty of Health Sciences, Universidad Europea de Canarias, C/Inocencio García 1, 38300 Santa Cruz de Tenerife, Spain.
Medicina (Kaunas). 2024 Mar 29;60(4):555. doi: 10.3390/medicina60040555.
: This study aimed to examine the responsiveness and concurrent validity of a serious game and its correlation between the use of serious games and upper limbs (UL) performance in Parkinson's Disease (PD) patients. : Twenty-four consecutive upper limbs (14 males, 8 females, age: 55-83 years) of PD patients were assessed. The clinical assessment included: the Box and Block test (BBT), Nine-Hole Peg test (9HPT), and sub-scores of the Unified Parkinson's Disease Rating-Scale Motor section (UPDRS-M) to assess UL disability. Performance scores obtained in two different tests (Ex. A and Ex. B, respectively, the Trolley test and Mushrooms test) based on leap motion (LM) sensors were used to study the correlations with clinical scores. : The subjective fatigue experienced during LM tests was measured by the Borg Rating of Perceived Exertion (RPE, 0-10); the BBT and 9HPT showed the highest correlation coefficients with UPDRS-M scores (ICCs: -0.652 and 0.712, < 0.05). Exercise A (Trolley test) correlated with UPDRS-M (ICC: 0.31, < 0.05), but not with the 9HPT and BBT tests (ICCs: -0.447 and 0.390, < 0.05), while Exercise B (Mushroom test) correlated with UPDRS-M (ICC: -0.40, < 0.05), as did these last two tests (ICCs: -0.225 and 0.272, < 0.05). The mean RPE during LM tests was 3.4 ± 3.2. The evaluation of upper limb performance is feasible and does not induce relevant fatigue. : The analysis of the ICC supports the use of Test B to evaluate UL disability and performance in PD patients, while Test A is mostly correlated with disability. Specifically designed serious games on LM can serve as a method of impairment in the PD population.
本研究旨在检验一款严肃游戏的反应性和同时效度，以及帕金森病（PD）患者使用严肃游戏与上肢（UL）功能之间的相关性。对24例连续的PD患者上肢（14例男性，8例女性，年龄55 - 83岁）进行了评估。临床评估包括：箱块测试（BBT）、九孔插板测试（9HPT）以及统一帕金森病评定量表运动部分（UPDRS - M）的子评分，以评估上肢功能障碍。基于Leap Motion（LM）传感器在两项不同测试（分别为示例A和示例B，即手推车测试和蘑菇测试）中获得的表现分数，用于研究与临床评分的相关性。通过Borg自觉用力程度分级（RPE，0 - 10）测量LM测试期间经历的主观疲劳；BBT和9HPT与UPDRS - M评分的相关系数最高（组内相关系数：-0.652和0.712，P < 0.05）。练习A（手推车测试）与UPDRS - M相关（组内相关系数：0.31，P < 0.05），但与9HPT和BBT测试不相关（组内相关系数：-0.447和0.390，P < 0.05），而练习B（蘑菇测试）与UPDRS - M相关（组内相关系数：-0.40，P < 0.05），与后两项测试也相关（组内相关系数：-0.225和0.272，P < 0.05）。LM测试期间的平均RPE为3.4±3.2。评估上肢功能是可行的，且不会引起相关疲劳。组内相关系数分析支持使用测试B评估PD患者的上肢功能障碍和表现，而测试A主要与功能障碍相关。专门设计的基于LM的严肃游戏可作为评估PD患者功能损害的一种方法。
