Zarmakoupi Panagiota, Psarris Alexandros, Karasmani Christina, Antsaklis Panagiotis, Theodora Marianna, Syndos Michael, Pampanos Andreas, Pappa Kalliopi I, Domali Ekaterini, Thomakos Nikolaos, Akinosoglou Karolina, Tsiakalos Aristotelis, Daskalakis George
1st Department of Obstetrics and Gynecology, Alexandra Hospital, 11527 Athens, Greece.
Department of Internal Medicine and Infectious Diseases, Medical School University of Patras, 26504 Patras, Greece.
Medicina (Kaunas). 2024 Apr 18;60(4):648. doi: 10.3390/medicina60040648.
Aerobic vaginitis (AV) is a distinct clinical entity characterized by inflammation and abnormal vaginal microflora. Often mistaken for bacterial vaginosis, AV remains relatively unknown and underdiagnosed. AV's understanding is evolving, with some experts suggesting it may primarily be an immunological disorder, the prevalence of which has a range of 7-13% in non-pregnant women and 4.1-8.3% during pregnancy. Pregnancy can affect susceptibility to vaginal infections, leading to adverse outcomes for the woman and the newborn. This review summarizes the correlation between AV and adverse pregnancy outcomes, particularly preterm birth, the leading cause of morbidity and mortality among neonates. An improved understanding of AV's impact on pregnancy outcomes can lead to early recognition, proper management, and effective interventions. While some studies support an association between AV and preterm labor, the existing knowledge of this relationship remains limited. The evidence suggests that AV may contribute to adverse pregnancy outcomes, mainly preterm birth, but further research is needed to establish a definitive link. Further studies are needed to investigate the underlying mechanisms and clarify AV's role in premature labor. A comprehensive understanding of AV's impact on pregnancy outcomes is crucial for early recognition, appropriate management, and effective interventions.
需氧菌性阴道炎（AV）是一种独特的临床病症，其特征为炎症和阴道微生物群异常。AV常被误诊为细菌性阴道病，目前仍相对不为人知且诊断不足。对AV的认识正在不断发展，一些专家认为它可能主要是一种免疫性疾病，在非孕妇中其患病率为7%-13%，在孕期为4.1%-8.3%。怀孕会影响对阴道感染的易感性，给女性和新生儿带来不良后果。本综述总结了AV与不良妊娠结局之间的相关性，特别是早产，早产是新生儿发病和死亡的主要原因。更好地了解AV对妊娠结局的影响有助于早期识别、妥善管理和有效干预。虽然一些研究支持AV与早产之间存在关联，但关于这种关系的现有知识仍然有限。证据表明，AV可能导致不良妊娠结局，主要是早产，但需要进一步研究来确定明确的联系。需要进一步研究以调查潜在机制并阐明AV在早产中的作用。全面了解AV对妊娠结局的影响对于早期识别、适当管理和有效干预至关重要。
